Therapy delivery method and system for implantable medical devices

• US 8,886,314 B2
• Filed: 09/26/2012
• Issued: 11/11/2014
• Est. Priority Date: 09/26/2012
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Crutchfield, Randolph E., Cabelka, Lonny V., Boone, Mark R., Rasmussen, Marshall J.
• Primary Examiner(s): Stoklosa, Joseph
• Assistant Examiner(s): Flory, Christopher A
• Application Number:
  US13/626,988
• Publication Number:
  US 20140088659A1
• Time in Patent Office: 776 Days
• Field of Search: 607/7, 607/9, 607/17, 607/37, 607/2, 607/5, 607/28, 607/29
• US Class Current: 607/28
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/3906 characterised by the form of the shockwave
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
• CPC Class Codes: A61N 1/3981 High voltage charging circuitry
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

The disclosure relates to an apparatus and method for inducing ventricular fibrillation in a patient to facilitate defibrillation threshold testing. The apparatus includes a plurality of output capacitors that are dynamically configurable in a selected stacking arrangement that facilitates delivery of energy for inducing the ventricular fibrillation. An output of the apparatus is coupled to patient electrodes and a threshold energy level delivered by the output capacitors is determined.

Claims

1. A method for testing a defibrillation threshold of an implantable medical device, comprising:

delivering a plurality of pacing pulses to a patient;

monitoring a cardiac signal to derive a T-wave of the cardiac signal responsive to the delivered pacing pulses;

identifying the ascending portion of the T-wave from the monitored cardiac signal; and

configuring a therapy delivery circuit for delivery of therapy, wherein a plurality of capacitors of the therapy delivery circuit are dynamically stacked in;

a parallel configuration for discharge of energy coincident with the ascending part of the T-wave to induce ventricular fibrillation, recharging the plurality of capacitors in the parallel configuration concurrently with the discharge of energy to induce ventricular fibrillation and prior to any reconfiguration of the dynamically stacked plurality of capacitors, and

subsequently reconfiguring the stacking of the plurality of capacitors prior to delivering stimulation therapy in response to an onset of the induced ventricular fibrillation, wherein the reconfiguration comprises stacking the plurality of capacitors from the parallel configuration to a series configuration.

2. The method of claim 1, further comprising detecting an onset of ventricular fibrillation triggered by the discharge of energy.

3. The method of claim 2, further comprising measuring an amount of the energy discharged from the plurality of capacitors to trigger the onset of ventricular fibrillation.

4. The method of claim 1, wherein the stacking of the plurality of capacitors is controlled to generate the stimulation waveform having a stepped leading edge.

5. The method of claim 1, wherein the dynamic reconfiguration comprises initiating delivery of a defibrillation therapy with discharge of a first of the plurality of capacitors and subsequently coupling each of the other of the plurality of capacitors in series with the first capacitor.

6. The method of claim 1, further comprising determining a lower limit of the discharged energy that terminates the ventricular fibrillation.

7. A method for testing a defibrillation threshold of an implantable medical device, comprising:

delivering a plurality of pacing pulses to a patient;

monitoring a cardiac signal to derive a T-wave of the cardiac signal responsive to the delivered pacing pulses;

identifying the ascending portion of the T-wave from the monitored cardiac signal; and

configuring a therapy delivery circuit for delivery of therapy, wherein a plurality of capacitors of the therapy delivery circuit are dynamically stacked in;

a parallel configuration for discharge of energy coincident with the ascending part of the T-wave to induce ventricular fibrillation, recharging the plurality of capacitors in the parallel configuration concurrently with the discharge of energy to induce ventricular fibrillation and prior to any reconfiguration of the dynamically stacked plurality of capacitors, and subsequently reconfiguring the plurality of capacitors prior to discharging of energy to terminate the ventricular fibrillation, wherein the reconfiguration of the plurality of capacitors comprises sequentially coupling each of the capacitors in series with a predefined interval being provided between the coupling of each of the capacitors.