Effectiveness of ventricular sense response in CRT
First Claim
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1. A method comprising:
- (a) delivering biventricular cardiac resynchronization therapy (CRT) to a heart at an atrio-ventricular (AV) interval;
(b) monitoring atrial contraction events;
(c) monitoring intrinsic ventricular contraction events;
(d) applying a biventricular CRT pacing stimulus on detection of an intrinsic ventricular contraction event to produce a ventricular-sense response (VSR);
(e) recording electrical activity of the heart in a defined time window centered or off centered on a time of delivery of the biventricular CRT pacing stimulus to obtain an electrogram of the VSR;
(f) comparing the electrogram of the VSR, or features thereof, to a template electrogram, or features thereof, of a pure biventricular paced beat to determine a similarity index between the electrogram of the VSR and the template electrogram;
(g) determining whether the similarity index meets or exceeds a predetermined threshold, wherein if the similarity index meets or exceeds the threshold steps (a)-(f) are repeated; and
(h) determining whether an atrial contraction event preceded the VSR if the threshold is not met or exceeded.
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Abstract
A method for monitoring the effectiveness of VSR and for taking action to improve the effectiveness of VSRs, if they are determined to be ineffective, includes comparing the a VSR evoked electrogram to a template electrogram of a pure biventricular paced CRT beat. If the electrograms, or features thereof, are similar, the VSR is determined to be effective. If the VSR is determined to be ineffective, the AV delay of biventricular CRT is shortened in a step-wise fashion in an incremental manner.
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10 Claims
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1. A method comprising:
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(a) delivering biventricular cardiac resynchronization therapy (CRT) to a heart at an atrio-ventricular (AV) interval; (b) monitoring atrial contraction events; (c) monitoring intrinsic ventricular contraction events; (d) applying a biventricular CRT pacing stimulus on detection of an intrinsic ventricular contraction event to produce a ventricular-sense response (VSR); (e) recording electrical activity of the heart in a defined time window centered or off centered on a time of delivery of the biventricular CRT pacing stimulus to obtain an electrogram of the VSR; (f) comparing the electrogram of the VSR, or features thereof, to a template electrogram, or features thereof, of a pure biventricular paced beat to determine a similarity index between the electrogram of the VSR and the template electrogram; (g) determining whether the similarity index meets or exceeds a predetermined threshold, wherein if the similarity index meets or exceeds the threshold steps (a)-(f) are repeated; and (h) determining whether an atrial contraction event preceded the VSR if the threshold is not met or exceeded. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A non-transitory computer readable medium for a system configured to deliver cardiac resynchronization therapy, the computer readable medium comprising instructions that, when implemented, cause the system to:
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(a) deliver biventricular cardiac resynchronization therapy (CRT) to a heart at an atrio-ventricular (AV) interval; (b) monitor atrial contraction events; (c) monitor intrinsic ventricular contraction events; (d) apply a biventricular CRT pacing stimulus on detection of an intrinsic ventricular contraction event to produce a ventricular-sense response (VSR); (e) record electrical activity of the heart in a defined time window centered or off centered on a time of delivery of the biventricular CRT pacing stimulus to obtain an electrogram of the VSR; (f) compare the electrogram of the VSR, or features thereof, and a template electrogram, or features thereof, of a pure biventricular paced beat to determine a similarity index between the electrogram of the VSR and the template electrogram; (g) determine whether the similarity index meets or exceeds a predetermined threshold, and repeat steps (a)-(f) if the similarity index meets or exceeds the threshold; and (h) determine whether an atrial contraction event preceded the VSR if the threshold is not met or exceeded. - View Dependent Claims (8, 9, 10)
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Specification