Therapy using perturbation and effect of physiological systems
First Claim
1. A method for using an implantable medical device, the method comprising:
- delivering electrical stimuli to an afferent nerve associated with the selected organ;
monitoring efferent electrical activity in an efferent nerve responsive to delivering electrical stimuli to the afferent nerve, wherein the monitored efferent electrical activity includes an indirect component of a compound action potential (CAP), wherein the indirect component is not in direct response to the delivered electrical stimuli; and
assessing a status of the selected organ based upon the indirect component.
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Accused Products
Abstract
Methods for treating a patient and further to devices for performing such treatment, e.g., methods and devices to perturb at least one physiological system and deliver therapy to the patient based on the effects of such perturbation. For example, a method for using an implantable medical device is disclosed that involves a method for using an implantable medical device delivering electrical stimuli to an afferent nerve associated with the selected organ. The efferent electrical activity is monitored in an efferent nerve responsive to delivering electrical stimuli to the afferent nerve, the monitored efferent electrical activity includes an indirect component of a compound action potential (CAP). A status of the selected organ is assessed based upon the indirect component.
323 Citations
20 Claims
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1. A method for using an implantable medical device, the method comprising:
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delivering electrical stimuli to an afferent nerve associated with the selected organ; monitoring efferent electrical activity in an efferent nerve responsive to delivering electrical stimuli to the afferent nerve, wherein the monitored efferent electrical activity includes an indirect component of a compound action potential (CAP), wherein the indirect component is not in direct response to the delivered electrical stimuli; and assessing a status of the selected organ based upon the indirect component. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for determining a fullness of a stomach using an implantable medical device, the method comprising:
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delivering electrical stimuli to an afferent nerve associated with the stomach; monitoring efferent electrical activity responsive to delivering electrical stimuli to the afferent nerve; assessing a status of the stomach in response to the monitored efferent electrical activity; and
amplifying a signal to the vagal nerve to indicate the stomach is partially full. - View Dependent Claims (18, 19, 20)
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Specification