Detecting, quantifying, and/or classifying seizures using multimodal data
First Claim
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1. A method for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
- providing a cardiac signal indicative of the patient'"'"'s heart activity;
determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate and at least one EKG morphology feature;
providing a kinetic signal indicative of body movement of the patient;
detecting an epileptic event based on a change in the at least one cardiac index selected from;
an increase in the patient'"'"'s heart rate;
a decrease in the patient'"'"'s heart rate;
ora change in said at least one EKG morphology feature; and
performing a further action based on said kinetic signal, wherein said further action is selected fromconfirming the detecting of the epileptic event;
ornot confirming the detecting of the epileptic event.
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Abstract
Methods, systems, and apparatus for detecting an epileptic event, for example, a seizure in a patient using a medical device. The determination is performed by providing an autonomic signal indicative of the patient'"'"'s autonomic activity; providing a neurologic signal indicative of the patient'"'"'s neurological activity; and detecting an epileptic event based upon the autonomic signal and the neurologic signal.
569 Citations
21 Claims
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1. A method for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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providing a cardiac signal indicative of the patient'"'"'s heart activity; determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate and at least one EKG morphology feature; providing a kinetic signal indicative of body movement of the patient; detecting an epileptic event based on a change in the at least one cardiac index selected from; an increase in the patient'"'"'s heart rate; a decrease in the patient'"'"'s heart rate;
ora change in said at least one EKG morphology feature; and performing a further action based on said kinetic signal, wherein said further action is selected from confirming the detecting of the epileptic event;
ornot confirming the detecting of the epileptic event. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 12)
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9. A method for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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providing a kinetic signal indicative of body movement of the patient; determining at least one kinetic index from said kinetic signal, wherein said at least one kinetic index is selected from a body posture, a body position, a fall, a parameter derived from an accelerometer signal selected from a movement, a frequency per unit time, a time interval between movements, a movement direction in at least one plane, an acceleration, a velocity, a force, or a change in one or more of the foregoing; providing a cardiac signal indicative of the patient'"'"'s heart activity; detecting an epileptic event based on said at least one kinetic index; and performing a further action based on said cardiac signal, wherein said further action is selected from confirming the detecting of the epileptic event;
ornot confirming the detecting of the epileptic event. - View Dependent Claims (10, 11, 13)
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14. A method for detecting an epileptic event based upon a patient'"'"'s cardiac signal and kinetic activity, comprising:
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providing a cardiac signal indicative of the patient'"'"'s heart activity; determining at least one cardiac index from the cardiac signal, wherein said at least one cardiac index is selected from a heart rate, an EKG morphology feature, an EKG rhythm feature, or an EKG wave interval feature; characterizing the at least one cardiac index as either indicative of an epileptic event or not indicative of an epileptic event; providing a kinetic signal indicative of body movement and type of body movement of the patient; characterizing the kinetic signal as either indicative of an epileptic event or not indicative of an epileptic event; and detecting an epileptic event only if both of the heart rate and the kinetic signal are indicative of an epileptic event. - View Dependent Claims (15, 16, 17, 18, 19)
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20. A medical device system for detecting an epileptic event based upon multimodal signals, comprising:
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a first sensor for detecting a first modal data and a second sensor for detecting a second modal data relating to a patient'"'"'s body, the first modal data comprising a kinetic signal and the second modal data comprising a cardiac signal of the patient'"'"'s body; and a medical device (MD) coupled to the patient'"'"'s body and operatively coupled to the first sensor and the second sensor;
the MD comprising;a kinetic signal module for receiving the kinetic signal; a cardiac signal module for receiving the cardiac signal; a detection module for determining whether an epileptic event has occurred based on; 1) detecting an epileptic event using one of said kinetic signal module and said cardiac signal module, and 2) confirming or not confirming said epileptic event using the other of said kinetic signal module and said cardiac signal module. - View Dependent Claims (21)
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Specification