Magnetic resonance diagnosis apparatus and data acquisition method of magnetic resonance spectroscopy

• US 8,890,521 B2
• Filed: 11/21/2011
• Issued: 11/18/2014
• Est. Priority Date: 11/26/2010
• Status: Active Grant

• Current Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Toshiba Medical Systems Corporation (Canon Inc.), Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Shinoda, Kensuke, Wakai, Satoshi
• Primary Examiner(s): Vargas, Dixomara
• Application Number:
  US13/300,922
• Publication Number:
  US 20120133360A1
• Time in Patent Office: 1,093 Days
• Field of Search: 324300-322
• US Class Current: 324/307
• CPC Class Codes: G01R 33/4838 using spatially selective suppression or saturation of MR signals
• CPC Class Codes: G01R 33/485 based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
• CPC Class Codes: G01R 33/543 Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription G01R33/546 takes precedence
• CPC Class Codes: G01R 33/56527 due to chemical shift effects
• CPC Class Codes: G01R 33/56536 due to magnetic susceptibility variations
• CPC Class Codes: G01R 33/56563 caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0 G01R33/56509, G01R33/56518, G01R33/56536 take precedence

Abstract

A magnetic resonance diagnosis apparatus automatically calculates an application region of a prepulse based on image data including a region of interest of an object generated before application of a prepulse. The prepulse is applied to the automatically calculated application region. A magnetic resonance signal is then received from a region including the region of interest, and magnetic resonance spectrum data is generated indicative of concentration distribution of metabolic substances in the region of interest.

Claims

1. A magnetic resonance diagnosis apparatus performing “

generation of image data of an object by magnetic resonance imaging”

, and magnetic resonance spectroscopy, the magnetic resonance diagnosis apparatus comprising;

an application region calculation unit configured to automatically calculate an application region of a spatially selective prepulse based on “

image data including a region of interest of the object generated by magnetic resonance imaging before application of a prepulse”

; and

a data generation unit configured to receive a magnetic resonance signal from a data acquisition region including the region of interest after applying the prepulse according to the application region automatically calculated by the application region calculation unit, and generate magnetic resonance spectrum data indicative of concentration distribution per metabolic substance in the region of interest based on the magnetic resonance signal.

2. The magnetic resonance diagnosis apparatus according to claim 1, further comprising:

a display unit configured to display the application region automatically calculated by the application region calculation unit, before determination of the application region of the prepulse; and

an input unit configured to receive input which determines the application region of the prepulse, after the application region automatically calculated by the application region calculation unit is displayed by the display unit;

wherein the data generation unit is configured to apply the prepulse to an application region determined by the input received by the input unit.

3. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the data generation unit is configured to apply the prepulse to the application region automatically calculated by the application region calculation unit.

4. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the application region calculation unit is configured to automatically calculate the application region of the prepulse according to the region of interest.

5. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the application region calculation unit is configured to determines whether the data generation unit applies the prepulse or not according to a position of the region of interest and the image data, and automatically calculate the application region of the prepulse if this determination result is affirmative.

6. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the application region calculation unit is configured to automatically calculate the application region of the prepulse based on a position of a specific tissue region extracted from the image data.

7. The magnetic resonance diagnosis apparatus according to claim 6,

wherein the application region calculation unit is configured to automatically calculate respective application regions of spatially selective prepulses whose number is according to a position of the region of interest and a position of the specific tissue region.

8. The magnetic resonance diagnosis apparatus according to claim 1, further comprising:

a display unit configured to display the application region automatically calculated by the application region calculation unit, before determination of the application region of the prepulse.

9. The magnetic resonance diagnosis apparatus according to claim 8,

wherein the application region calculation unit is configured to extract “

a region which is adjacent to a bone of the object and indicates a stronger magnetic resonance signal than its adjacent region in the image data”

or “

a region indicating a weaker magnetic resonance signal than its adjacent region in the image data due to airspace in the object”

as a region to be avoided; and

the display unit is configured to display the region to be avoided and the application region automatically calculated by the application region calculation unit.

10. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the application region calculation unit is configured to extract “

a region which is adjacent to a bone of the object and indicates a stronger magnetic resonance signal than its adjacent region in the image data”

or “

a region indicating a weaker magnetic resonance signal than its adjacent region in the image data due to airspace in the object”

as a region to be avoided, set a judging frame defined by extending an outer border of the data acquisition region, and automatically calculate the application region of the prepulse when the judging frame overlaps on the region to be avoided.

11. The magnetic resonance diagnosis apparatus according to claim 10,

wherein the application region calculation unit is configured to calculate positions of a plurality of intersection points between the judging frame and the region to be avoided, automatically calculate an application region of each of spatially selective prepulses respectively corresponding to straight lines each passing two of the intersection points so that each application region is aligned with one of the straight lines, when the judging frame overlaps on the region to be avoided.

12. The magnetic resonance diagnosis apparatus according to claim 11,

wherein the application region calculation unit is configured to extract “

a region which is adjacent to a bone of the object and indicates a stronger magnetic resonance signal than its adjacent region in the image data”

as the region to be avoided, when a cephalic part of the object is set as the region of interest.

13. The magnetic resonance diagnosis apparatus according to claim 11,

wherein the application region calculation unit is configured to automatically calculate an application region of each of spatially selective prepulses whose number is according to input information setting the number unlimited or limited, when at least a part of the data acquisition region overlaps on the region to be avoided.

14. The magnetic resonance diagnosis apparatus according to claim 10,

wherein the application region calculation unit is configured to

(a) extract the region to be avoided from each of cross-sections including the region of interest, image data of the cross-sections are generated by magnetic resonance imaging before application of the prepulse;

(b) set the judging frame for each of the cross-sections;

(c) determine whether the judging frame overlaps on an outer border of the region to be avoided in at least one of the cross-sections or not; and

(d) automatically calculate the application region of the prepulse based on intersection points between the judging frame and the outer border of the region to be avoided, when the determination result is affirmative.

15. The magnetic resonance diagnosis apparatus according to claim 14,

wherein the application region calculation unit is configured to

(a) calculate a position of an intersection point between the judging frame and the outer border of the region to be avoided in a cross-section on which the judging frame overlaps on the outer border of the region to be avoided, as a criterion point;

(b) calculate a tangent line circumscribed to the outer border of the region to be avoided at the criterion point in “

a cross-section which includes the criterion point and is orthogonal to the cross-section on which the judging frame overlaps on the outer border of the region to be avoided”

; and

(c) automatically calculate the application region of the prepulse based on the tangent line.

16. The magnetic resonance diagnosis apparatus according to claim 1, further comprising:

a display unit configured to display a scout image for setting a range of the data acquisition region; and

an input unit configured to receive input which sets the range of the data acquisition region using the scout image as a criterion;

wherein the application region calculation unit is configured to extract “

regions which are adjacent to a bone of the object and indicate a stronger magnetic resonance signal than its adjacent region in the image data”

or “

regions indicating a weaker magnetic resonance signal than its adjacent region in the image data due to airspace in the object”

from image data respectively corresponding to cross-sections each including the region of interest, as regions to be avoided, and calculate a combined region of the regions to be avoided through the cross-sections;

the display unit is configured to use one of cross-sectional images of the cross-sections as the scout image, and superimpose and display the combined region on this scout image; and

the data generation unit is configured to receive the magnetic resonance signal from the data acquisition region whose range is based on the input to the input unit.

17. The magnetic resonance diagnosis apparatus according to claim 1,

wherein the application region calculation unit is configured to automatically calculate the application region of the prepulse according to a position of the region of interest, based on image data of a fat weighted image including the region of interest.

18. A magnetic resonance diagnosis apparatus comprising:

an extraction unit configured to extract a region of a specific tissue from image data including a region of interest of an object generated by magnetic resonance imaging, as a region to be avoided;

a display unit configured to display the region to be avoided;

an input unit configured to receive input which sets a range of a data acquisition region;

an input restriction unit configured to set a judging frame defined by extending an outer border of the data acquisition region, and then, “

restrict the input to the input unit so as to separate the judging frame from the region to be avoided”

or “

inform that the judging frame overlaps on the region to be avoided in such case”

; and

a data generation unit configured to receive a magnetic resonance signal from the data acquisition region after determining the range of the data acquisition region based on the input to the input unit, and generate magnetic resonance spectrum data indicative of concentration distribution per metabolic substance in the data acquisition region based on the magnetic resonance signal.

19. The magnetic resonance diagnosis apparatus according to claim 18,

wherein the extraction unit is configured to extract “

a region indicating a stronger magnetic resonance signal than its adjacent region in the image data”

or “

a region indicating a weaker magnetic resonance signal than its adjacent region in the image data due to airspace in the object”

, as the region to be avoided; and

the display unit is configured to display the image data including the region of interest as an image with the region to be avoided superimposed on this displayed image.

20. A data acquisition method of magnetic resonance spectroscopy comprising the steps of:

calculating an application region of a spatially selective prepulse based on “

image data including a region of interest of an object generated by magnetic resonance imaging”

automatically, before application of a prepulse;

receiving a magnetic resonance signal from a data acquisition region including the region of interest, after applying the prepulse according to the application region automatically calculated; and

generating magnetic resonance spectrum data indicative of concentration distribution per metabolic substance in the region of interest based on the magnetic resonance signal.