Sampling plate

• US 8,894,832 B2
• Filed: 03/30/2011
• Issued: 11/25/2014
• Est. Priority Date: 03/30/2010
• Status: Active Grant

• Current Assignee: Jabil Circuit Limited (Jabil Inc.)
• Original Assignee: Jabil Circuit Limited (Jabil Inc.)
• Inventors: Bryan, Matthew Robert
• Primary Examiner(s): Ball, J. Christopher
• Application Number:
  US13/637,813
• Publication Number:
  US 20130020198A1
• Time in Patent Office: 1,336 Days
• Field of Search: 204/400, 204/415, 422/547
• US Class Current: 204/415
• CPC Class Codes: B01L 2200/04 Exchange or ejection of cartridges, containers or reservoirs
• CPC Class Codes: B01L 2200/0642 Filling fluids into wells by specific techniques
• CPC Class Codes: B01L 2200/0684 Venting, avoiding backpressure, avoid gas bubbles
• CPC Class Codes: B01L 2200/12 Specific details about manufacturing devices
• CPC Class Codes: B01L 2300/027 Digital display, e.g. LCD, LED
• CPC Class Codes: B01L 2300/0681 Filter
• CPC Class Codes: B01L 2300/0816 Cards, e.g. flat sample carriers usually with flow in two horizontal directions
• CPC Class Codes: B01L 2300/165 Specific details about hydrophobic, oleophobic surfaces
• CPC Class Codes: B01L 3/502715 characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
• CPC Class Codes: B01L 3/502723 characterised by venting arrangements
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

The present invention relates to a sampling plate. In particular the invention relates to a sampling plate for measuring certain selected properties of a liquid sample, such as the glucose levels in a blood sample. Sampling plates of the present invention have a sample zone (20) for receiving a liquid sample which is surrounded by an air porous body (4). The air porous body (4) acts to receive air from the sample zone (20) as it is displaced by an incoming liquid sample, thereby allowing efficient spreading of the liquid sample.

Claims

1. A sampling plate, comprising:

a sample zone for receiving a liquid sample, the sample zone comprising at least two discrete testing zones and a separation means comprising a hydrophobic zone for separating the liquid sample into at least two discrete samples occupying a respective testing zone; and

an air porous body which is in fluid communication with the sample zone;

wherein the air porous body is arranged to receive air displaced from the sample zone as the liquid sample is received into the sample zone.

2. The sampling plate as claimed in claim 1, wherein the air porous body is substantially impermeable to water.

3. The sampling plate as claimed in claim 1, wherein the air porous body is arranged to hold the liquid sample within the sample zone.

4. The sampling plate as claimed in claim 1, wherein the air porous body is located substantially around the perimeter of the sample zone.

5. The sampling plate as claimed in claim 1, wherein the air porous body comprises hydrophobic material.

6. The sampling plate as claimed in claim 1, wherein the air porous body has a porosity of 0.2 or more.

7. The sampling plate as claimed in claim 1, wherein the air porous body comprises a mesh.

8. The sampling plate as claimed in claim 7 wherein the mesh comprises polyether ether ketone (PEEK), polypropylene (PP), polyester (PET), polyvinylidene fluoride (PVDF), ethylene chlorotrifluoroethylene (ECTFE), ethylene co-tetrafluoroethylene (ETFE), nylon (polyamide), or fluorinated ethylene-propylene (FEP).

9. The sampling plate as claimed in claim 1, wherein the air porous body is a porous layer of the sampling plate, the layer comprising an empty portion arranged to receive and contain the liquid sample.

10. The sampling plate as claimed in claim 1, the sample zone comprises at least one hydrophilic floor for containing the liquid sample.

11. The sampling plate as claimed in claim 1, comprising a loading port located on a top face of the sampling plate.

12. A sampling plate, comprising:

a sample zone for receiving a liquid sample;

an air porous but water impermeable body which is in fluid communication with the sample zone, the air porous body being arranged to receive air displaced from the sample zone as the liquid sample is received into the sample zone;

a loading port for loading the liquid sample; and

a loading path between the loading port and sample zone along which the liquid sample can travel towards the sample zone;

wherein the sample zone comprises;

at least two discrete testing zones, each defined by a well, having a hydrophobic boundary lying between the at least two testing zones; and

a raised hydrophobic loading platform located towards a central region lying between all the respective testing zones, the loading platform being arranged to first receive the liquid sample before distributing the liquid sample amongst the respective testing zones;

wherein each testing zone comprises;

a hydrophilic portion; and

a pair of electrodes which is bridged, in use, by the liquid sample in a testing zone.

13. A sampling plate, comprising:

a sample zone for receiving a liquid sample;

an air porous body which is in fluid communication with the sample zone; and

at least one pair of electrodes arranged to permit an electrochemical measurement to be taken in respect of the liquid sample, wherein the air porous body is arranged to receive air displaced from the sample zone as the liquid sample is received into the sample zone.