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Method and apparatus for therapies of the cardiovascular and cardiorenal system

  • US 8,897,879 B2
  • Filed: 11/02/2012
  • Issued: 11/25/2014
  • Est. Priority Date: 11/04/2011
  • Status: Active Grant
First Claim
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1. A method of controlling respiration depth or respiration rate through an implanted medical electrical lead having an electrode for pacing and sensing, the method comprising:

  • delivering electrical stimulation through an electrode proximate phrenic nerve tissue, andeliciting modulating respiration in response to electrical stimulation of the phrenic nerve, the modulating respiration asynchronously modifies intrinsic respiration,wherein glomerular filtration rate (GFR) is improved by about 10% compared to another GFR before any phrenic nerve stimulation has occurred.

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