Ophthalmic lenses modified with functional groups and methods of making thereof
First Claim
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1. A method for making an ophthalmic lens comprising:
- contacting the lens with a solution comprising a functional compound in an alcohol, a ketone, an ether, an aldehyde, or any combination thereof, wherein the functional compound comprises at least one group capable of forming a covalent bond with the lens upon exposing the lens to irradiation and/or heat, wherein the lens comprises a silicon hydrogel; and
irradiating and/or heating the lens produced in step (a) to covalently attach the functional compound to the lens, wherein the lens subjected to step a) and step b) treatment has an UVB absorbing capability characterized by having an UVB transmittance being at least 50 percentage lower than that of the lens subjected to only step a) treatment when both lenses are extracted with methyl ethyl ketone for about 20 hours.
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Abstract
Described are methods for covalently attaching one or more functional compounds to an ophthalmic lens. The method involves (a) contacting the lens with a functional compound, wherein the functional compound comprises at least one group capable of forming a covalent bond with the lens upon exposing the lens to irradiation and/or heat; and (b) irradiating and/or heating the lens produced in step (a) to covalently attach the functional compound to the lens. Also described herein are ophthalmic lens produced by the methods described herein.
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15 Claims
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1. A method for making an ophthalmic lens comprising:
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contacting the lens with a solution comprising a functional compound in an alcohol, a ketone, an ether, an aldehyde, or any combination thereof, wherein the functional compound comprises at least one group capable of forming a covalent bond with the lens upon exposing the lens to irradiation and/or heat, wherein the lens comprises a silicon hydrogel; and irradiating and/or heating the lens produced in step (a) to covalently attach the functional compound to the lens, wherein the lens subjected to step a) and step b) treatment has an UVB absorbing capability characterized by having an UVB transmittance being at least 50 percentage lower than that of the lens subjected to only step a) treatment when both lenses are extracted with methyl ethyl ketone for about 20 hours. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification