Clot retrieval system

• US 8,900,265 B1
• Filed: 01/03/2014
• Issued: 12/02/2014
• Est. Priority Date: 01/03/2014
• Status: Active Grant

• Current Assignee: Legacy Ventures, LLC
• Original Assignee: Legacy Ventures, LLC
• Inventors: Ulm, Arthur John III
• Primary Examiner(s): MCEVOY, THOMAS M
• Application Number:
  US14/147,491
• Time in Patent Office: 333 Days
• Field of Search: 606/192, 606/194, 606/200
• US Class Current: 606/200
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop

Abstract

The present invention relates to a system for removing obstructions and other objects within a blood vessel or other interior lumen of an animal. The system may be deployed in the lumen from a catheter and includes a pull wire having a proximal end and a distal end, and a distal body. Optionally, the distal body includes a plurality of memory metal strips that form a closeable claw that is used to capture the obstruction. Optionally, the memory metal strips are connected to a proximal hub that is slideable along at least a segment of the pull wire and the memory metal strips are moved towards each other and towards the pull wire by moving the proximal hub distally towards a stationary distal hub, which in turn, causes the claw to close and capture the obstruction. The present invention also relates to methods of making and using such systems.

Claims

1. A system for removing objects adhered to a wall of an interior lumen of an animal, the system comprising:

a pull wire having a proximal end and a distal end;

a distal body attached to said pull wire, said distal body comprising an interior, an exterior, a proximal end, a distal end, a plurality of proximal memory metal strips located at said proximal end, a proximal hub located in said distal body interior, and a distal hub located distal relative to said proximal hub, said distal body having a relaxed state wherein said distal body has a first height and width, and a collapsed state wherein said distal body has a second height and width, said second height less than said first height, said second width less than said first width;

a catheter having an interior, a proximal end leading to said interior and a distal end leading to said interior, said catheter comprised of a biocompatible material and configured to envelope said distal body when said distal body is in said collapsed state;

wherein each of said proximal memory metal strips has a proximal end and a distal end,

wherein, in said relaxed state, each of said proximal ends of said memory metal strips is located proximal relative to said proximal hub,

wherein, in said relaxed state, said proximal ends of said proximal memory metal strips are configured to move towards each other and towards said pull wire, while remaining a fixed distance from said distal hub, by moving said proximal hub distally towards said distal hub,

wherein, in said relaxed state, said proximal ends of said proximal memory metal strips are configured to move away from each other and away from said pull wire, by moving said proximal hub proximally and away from said distal hub, and

wherein said proximal memory metal strips are configured to remove an object adhered to a wall of an interior lumen of an animal.

2. The system of claim 1 further comprising a plurality of memory metal connector strips, the plurality of memory metal connector strips each having a proximal end attached to a proximal memory metal strip and a distal end attached to said proximal hub and further wherein, in said relaxed state, said proximal ends of said memory metal connector strips are configured to move towards said pull wire upon moving said proximal hub distally towards said distal hub and said movement of said memory metal connector strips is configured to cause said proximal ends of said proximal memory metal strips to move towards each other and towards said pull wire.

3. The system of claim 2, wherein said connector strips are integral with said proximal hub.

4. The system of claim 1, wherein said proximal hub is a tube having an aperture and said pull wire passes through said aperture.

5. The system of claim 4, wherein, in said relaxed state, said proximal hub is slideable along at least a segment of said pull wire distal to said proximal hub and further wherein said distal hub is attached to said pull wire such that said distal hub is not slideable along said pull wire.

6. The system of claim 1, wherein, in said relaxed state, said proximal memory metal strips are distributed substantially evenly about a perimeter of the distal body.

7. The system of claim 1, wherein said distal hub is a tube having an aperture, wherein said pull wire extends from said proximal hub to said distal hub and further wherein said distal hub is attached to said pull wire such that said distal hub is not slideable along said pull wire.

8. The system of claim 1, wherein said pull wire extends from said proximal hub to said distal hub and further wherein said distal hub is attached to said pull wire such that said distal hub is not slideable along said pull wire.

9. The system of claim 1, wherein said distal body further comprises a lead wire extending distally from said distal hub.

10. The system of claim 1, wherein said distal body comprises a basket comprised of a plurality of memory metal strips distal relative to said proximal memory metal strips.

11. The system of claim 10, wherein said distal hub, said proximal hub, and said distal basket are comprised of a nitinol having the same material composition.

12. The system of claim 1, wherein said distal body further comprises an x-ray marker configured to be detected by an x-ray radiation of 0.01 mrem when the distal body is located in a cranial blood vessel inside the body of a human and the x-ray is taken from outside the human'"'"'s body.

13. The system of claim 1, wherein said proximal memory metal strips form a claw, said claw having a closeable proximal end formed by said proximal ends of said proximal memory metal strips.

14. The system of claim 13, wherein between 2 and 4 proximal memory metal strips form said claw.

15. The system of claim 1, wherein said distal body, in said relaxed state, has a tapered shape in which the distal body height and width decrease from the proximal end to the distal end.

16. The system of claim 15, wherein said distal body, in said relaxed state, has a bullet shape.

17. The system of claim 1, wherein said proximal and said distal hubs are generally cylindrical in shape and each has an outer diameter and an inner diameter, the inner diameter forming apertures of the proximal and distal hubs and further wherein the outer diameters of the proximal and distal hubs are substantially the same size and further wherein the inner diameters of the proximal and distal hubs are substantially the same size.

18. The system of claim 17, further wherein the outer diameters of the proximal and distal hubs are from about 0.011 inches to about 0.054 inches, and further wherein the inner diameters of the proximal and distal hubs are from about 0.008 inches to about 0.051 inches.

19. The system of claim 1, wherein the pull wire is generally cylindrical and further wherein the diameter of the pull wire is between about 0.008 inches and about 0.051 inches.

20. The system of claim 1, wherein said proximal memory metal strips have a length of between about 10 and about 60 millimeters.

21. The system of claim 1, wherein the first height and first width of the distal body are between about 2 millimeters and about 6 millimeters.

22. The basket system of claim 1, wherein the proximal memory metal strips are configured to separate a clot from a blood vessel wall.

23. The system of claim 1, wherein said proximal ends of said proximal memory metal strips are not connected to each other.

24. The system of claim 1, wherein, in said relaxed state, said interior of said distal body is hollow.

25. A method of removing an object adhered to a wall of an interior lumen of an animal, the method comprising the steps of:

a) providing the system of claim 1;

b) positioning the system in said lumen;

c) deploying said distal body from said distal end of said catheter;

d) allowing said height and width of said distal body to increase; and

e) moving said proximal memory metal strips towards each other and said pull wire so as to capture said object.

26. The method of claim 25, wherein said distal body is deployed distal to said object.

27. The method of claim 25, wherein said method further comprises moving said proximal hub distally and closer to said distal hub so as to capture said object.

28. The method of claim 27, wherein said interior lumen is an intracranial artery and said object is a blood clot.

29. The method of claim 28, wherein said method further comprises using said blood clot to move said proximal hub toward said distal hub and exert tension on said proximal memory metal strips.

30. The method of claim 28, wherein said method further comprises using a tube to move said proximal hub toward said distal hub and exert tension on said proximal memory metal strips.