Machine for the preparation of pharmaceutical products

• US 8,905,086 B2
• Filed: 10/26/2012
• Issued: 12/09/2014
• Est. Priority Date: 07/26/2006
• Status: Active Grant

• Current Assignee: Omnicell Srl (Omnicell Incorporated)
• Original Assignee: Health Robotics S.r.l (Omnicell Incorporated)
• Inventors: Giribona, Paolo, Rainer, Werner, Baldassari, Daniele, Gabbarrini, Alferino, Paluselli, Pietro
• Primary Examiner(s): ARNETT, NICOLAS ALLEN
• Application Number:
  US13/661,405
• Publication Number:
  US 20130192716A1
• Time in Patent Office: 774 Days
• Field of Search: 141/2, 141/10, 141/27, 141/51, 141/63, 141/85, 141/114, 141/248, 141313-315
• US Class Current: 141/27
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/16 Holders for containers
• CPC Class Codes: A61J 1/20 Arrangements for transferring or mixing fluids, e.g. from vial to syringe
• CPC Class Codes: A61J 3/002 Compounding apparatus specially for enteral or parenteral nutritive solutions bottling liquids B67C
• CPC Class Codes: B01F 2035/3512 Fluid sealings, e.g. using liquids or air under pressure which is leaking into the mixing receptacle
• CPC Class Codes: B01F 2101/22 Mixing of ingredients for pharmaceutical or medical compositions
• CPC Class Codes: B01F 29/31 the containers being supported by driving means, e.g. by rotating rollers
• CPC Class Codes: B01F 29/321 of test-tubes or the like
• CPC Class Codes: B01F 29/33 by imparting a combination of movements to two or more containers
• CPC Class Codes: B01F 29/40353 being perpendicular axes
• CPC Class Codes: B01F 29/40363 having perpendicular axes
• CPC Class Codes: B01F 33/84 Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
• CPC Class Codes: B01F 33/848 using data, i.e. barcodes, 3D codes or similar type of tagging information, as instruction or identification codes for controlling the dispensing and mixing operations
• CPC Class Codes: B01F 35/146 Working under sterile conditions; Sterilizing the mixer or parts thereof
• CPC Class Codes: B01F 35/422 having a jaw-type or finger-type shape
• CPC Class Codes: B65B 1/04 Methods of, or means for, filling the material into the containers or receptacles
• CPC Class Codes: B65B 43/46 using grippers
• CPC Class Codes: B65B 43/465 for bags

Abstract

A machine for the preparation of pharmaceutical products is provided with a gripping and carrier device to transfer at least one container between a magazine and a dosage station for the preparation of a pharmaceutical product, and a box-type holding frame defining a chamber for the housing of magazine, gripping and carrier device, and dosage station; the chamber displaying an access aperture to magazine and being crossed by a sterile air flow adapted to avoid the entry of air from the external environment through aperture itself.

Claims

1. A machine for the preparation of pharmaceutical products comprising a magazine for at least one container, which displays at least one neck for the transfer of fluids from and to container, and is provided with an adapter member mounted on the neck itself;

a dosage station for the preparation of a pharmaceutical product comprising at least one pharmaceutical compound and at least one diluent; and

gripping and carrier means adapted to grab the adapter member to transfer the container between the magazine and the dosage station;

wherein the adapter member comprises two jaws, which are mobile between a clamping position and a release position of said neck, and locking means to lock the jaws themselves in said clamping position;

wherein the jaws are reciprocally hinged to rotate one with respect to the other about a fulcrum axis; and

wherein the locking means comprise a seat obtained in a first of said two jaws, a pin which is substantially parallel to said fulcrum axis, and a support crank holding the pin, which is hinged to a second of said two jaws to displace the pin itself from and to an engagement working position of said seat.

2. The machine according to claim 1, wherein said jaws display a thickness thinner than the length of said neck.

3. The machine according to claim 1, wherein said seat, which is obtained in said first jaw, and a locking member, which is carried by said second jaw and is mobile from and to an engagement working position of the seat itself.

4. The machine according to claim 1, wherein at least one of the jaws is configured to be coupled with at least one support device.

5. The machine according to claim 1, wherein said container is a plastic material bag.

6. The machine according to claim 1, wherein said container is comprised of a plastic material.

7. A machine for the preparation of pharmaceutical products comprising a magazine for at least one container, which displays at least one neck for the transfer of fluids from and to container, and is provided with an adapter member mounted on the neck itself;

a dosage station for the preparation of a pharmaceutical product comprising at least one pharmaceutical compound and at least one diluent; and

a gripping and carrier mechanism adapted to grab the adapter member to transfer the container between the magazine and the dosage station; and

wherein the adapter member comprises two jaws, which rotate mobile between a clamping position and a release position of said neck, and a locking mechanism to lock the jaws themselves in said clamping position;

wherein the jaws are reciprocally hinged to rotate one with respect to the other about a fulcrum axis; and

wherein the locking mechanism comprises a seat obtained in a first of said two jaws, a pin which is substantially parallel to said fulcrum axis, and a support crank holding the pin, which is hinged to a second of said two jaws to displace the pin itself from and to an engagement working position of said seat.