Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
First Claim
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1. A method for treating Type-2 diabetes, obesity, or insulin-resistance syndrome, or for causing weight loss, in a mammal in need thereof, the method comprising administering to the mammal a therapeutically effective amount of a PPF polypeptide to treat obesity, Type-2 diabetes, or insulin-resistance syndrome, or to cause weight loss, wherein the PPF polypeptide comprises the amino acid sequence of Formula (VII) (SEQ ID NO:
- 482);
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Abstract
The present invention provides novel Pancreatic Polypeptide Family (“PPF”) polypeptides and methods for their use.
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8 Claims
- 1. A method for treating Type-2 diabetes, obesity, or insulin-resistance syndrome, or for causing weight loss, in a mammal in need thereof, the method comprising administering to the mammal a therapeutically effective amount of a PPF polypeptide to treat obesity, Type-2 diabetes, or insulin-resistance syndrome, or to cause weight loss, wherein the PPF polypeptide comprises the amino acid sequence of Formula (VII) (SEQ ID NO:
Specification