Charged particle radiation therapy

• US 8,907,311 B2
• Filed: 11/22/2011
• Issued: 12/09/2014
• Est. Priority Date: 11/18/2005
• Status: Active Grant

• Current Assignee: Mevion Medical Systems Incorporated
• Original Assignee: Mevion Medical Systems Incorporated
• Inventors: Gall, Kenneth, Rosenthal, Stanley, Row, Gordon, Ahearn, Michael
• Primary Examiner(s): Wells, Nikita
• Application Number:
  US13/303,110
• Publication Number:
  US 20120126140A1
• Time in Patent Office: 1,113 Days
• Field of Search: 250/505.1, 250/492.3, 250/491.1, 250/396.R, 315/503, 315/502, 315/500, 376/112, 560/1
• US Class Current: 250/505.1
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: H05H 13/02 Synchrocyclotrons, i.e. frequency modulated cyclotrons
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 2007/043 for beam focusing
• CPC Class Codes: H05H 7/04 Magnet systems , e.g. undulators, wigglers free-electron laser H01S3/0903; Energisation thereof

Abstract

A system includes a patient support and an outer gantry on which an accelerator is mounted to enable the accelerator to move through a range of positions around a patient on the patient support. The accelerator is configured to produce a proton or ion beam having an energy level sufficient to reach a target in the patient. An inner gantry includes a robotic arm capable of directing an aperture for directing the proton or ion beam towards the target.

Claims

1. A system comprising:

a patient support;

an outer gantry comprising legs between which a particle accelerator is mounted to enable the particle accelerator to move through a range of positions around a patient on the patient support, the particle accelerator being configured to produce a proton or ion beam having an energy level sufficient to reach a target in the patient; and

a robotic arm that is between the legs of the outer gantry and that is between the particle accelerator and the patient, the robotic arm being configured to hold an aperture and to position the aperture between the particle accelerator and the patient in order to direct the proton or ion beam to the patient, the robotic arm being configured to move the aperture in three dimensions relative to the patient.

2. The system of claim 1, wherein the aperture is configured to alter the proton or ion beam.

3. The system of claim 2, wherein the aperture is configured to alter the proton or ion beam by collimating the proton or ion beam.

4. The system of claim 2, wherein the aperture is configured to alter the proton or ion beam by changing a size of the proton or ion beam.

5. The system of claim 2, wherein the aperture is configured to alter the proton or ion beam by changing a shape of the proton or ion beam.

6. The system of claim 4, wherein the aperture is configured to change the size of the proton or ion beam to treat a tumor of a specific size.

7. The system of claim 5, wherein the aperture is configured to change the shape of the proton or ion beam to treat a tumor of a specific shape.

8. The system of claim 4, wherein the aperture is configured to collimate the proton or ion beam.

9. The system of claim 1, wherein the aperture comprises a multi-leaf collimator.

10. The system of claim 2, wherein the robotic arm is computer controlled.

11. The system of claim 1, wherein the outer gantry is controllable to a precision that is at or greater than a millimeter.

12. The system of claim 1, wherein the robotic arm is manually controllable.

13. The system of claim 1, wherein the patient support is movable relative to the outer gantry.

14. The system of claim 1, wherein the patient support is movable relative to the robotic arm.

15. The system of claim 1, wherein the patient support is configured for rotation about a patient axis of rotation.

16. The system of claim 15, wherein the patient axis of rotation is vertical.

17. The system of claim 15, wherein the patient axis of rotation contains an isocenter in the patient on the patient support.

18. A system comprising:

a gantry comprising legs between which a particle beam accelerator is mounted, the legs being movable to move the particle beam accelerator to positions above and below a target, the particle beam accelerator for directing a particle beam towards the target;

an aperture located between the particle beam accelerator and the target, the aperture for modifying the particle beam; and

a robotic arm that is between the legs of the gantry and between the particle beam accelerator and the target, the robotic arm for holding the aperture, the robotic arm being movable relative to the target;

wherein the robotic arm is computer controlled to move the aperture in three dimensions relative to the target in order to position the aperture.

19. The system of one of claim 18, wherein the particle beam accelerator is a synchrocyclotron.

20. The system of claim 18, further comprising a processing device programmed to control movement of the gantry and the robotic arm and optionally a size and/or shape of the aperture.

21. The system of claim 20, wherein the processing device is configured to control movement of the gantry and the robotic arm to substantially align the proton or ion beam with the aperture.

22. The system of claim 18, wherein the aperture is configured to collimate the proton or ion beam.

23. The system of claim 18, wherein the target is movable relative to the gantry and the robotic arm.

24. The system of claim 18, wherein the system is configured to move the gantry and the robotic arm for enabling targeting of tumors and/or other treatment areas on a patient at the target.

25. The system of claim 18, further comprising:

a beam formation system comprising scanning elements located where the particle beam exits the particle accelerator.

26. The system of claim 18, further comprising:

active scanning elements located between the aperture and a point at which the particle beam exits the particle accelerator.

27. The system of claim 18, further comprising:

active scanning elements located along an output path of the particle beam from the particle accelerator.

28. The system of claim 18, wherein a size of the aperture is controllable to be increased or to be decreased.

29. The system of claim 18, wherein a shape of the aperture is alterable.

30. The system of claim 29, wherein the shape of the aperture is alterable between a circular shape, an oval shape, and a polygonal shape.

31. The particle beam therapy system of claim 18, wherein the particle accelerator is a synchrocyclotron that is configured to output the particle beam essentially directly from the synchrocyclotron to a patient at the target.

32. The particle beam therapy system of claim 31, wherein the synchrocyclotron comprises a particle source that is interrupted, the particle source comprising a tube containing plasma from which particles for the particle beam are extracted, the tube being interrupted such that all of the tube is removed at an acceleration region where the particles are extracted from the plasma.