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Noninvasive measurement of chemical substances

  • US 8,914,089 B2
  • Filed: 06/13/2008
  • Issued: 12/16/2014
  • Est. Priority Date: 02/23/2001
  • Status: Expired due to Fees
First Claim
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1. An apparatus for noninvasive measurement of the concentration of at least one substance in conjunctival tissue of the eye, said apparatus comprising:

  • a source of electromagnetic radiation optically coupled to a remote transmitter, said remote transmitter being configured to irradiate one side of the conjuctival tissue of the eye,a detecting device optically coupled with a remote receiver, said remote receiver being configured to be located on an opposite side from the one side of the conjuctival tissue and exteriorly of the eye and collecting electromagnetic radiation emitted by the substance being measured in the conjuctival tissue,said detecting device being configured for detecting an intensity of the electromagnetic radiation and providing an output signal representative of the detected intensity of said radiation,the remote receiver and the remote transmitter being maintained spaced from each other and located diametrically opposed to each other at corresponding terminal ends of two arms, said two arms extending from the source of electromagnetic radiation and from the detecting device, respectively, said two arms being bent outwardly from the source of electromagnetic radiation and from said detecting device, said two arms then being bent inwardly and terminating at said remote receiver and said remote transmitter, respectively, in a forceps configuration to space the remote receiver and said remote transmitter from each other, andan analyzer/processor configured to calculate a concentration of the substance of interest in the conjunctival tissue of the eye from the output signal.

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