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Method for treating depression by indirectly stimulating raphe nuclei

  • US 8,914,120 B2
  • Filed: 09/26/2013
  • Issued: 12/16/2014
  • Est. Priority Date: 10/01/2012
  • Status: Active Grant
First Claim
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1. A method for treating a patient suffering from depression, the method comprising:

  • applying electrical stimulation energy from at least one electrode configured for implantation within the epidural space of the patient, to afferent nerve fibers leading to the medial preoptic region of the hypothalamus of the patient, thereby activating serotonin in the raphe nuclei to treat depression, wherein the afferent nerve fibers are at a sacral spinal level in the range of S1-S3.

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