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Arrangement and method using microsensors for measuring cell vitalities

  • US 8,916,035 B2
  • Filed: 09/29/2010
  • Issued: 12/23/2014
  • Est. Priority Date: 09/30/2009
  • Status: Active Grant
First Claim
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1. A device to measure cell vitalities, comprising:

  • a semiconductor chip;

    a sensor array formed on one surface of the semiconductor chip, the sensor array comprising a plurality of sensors, each sensor producing a measurement signal and comprising a working electrode, the sensor array being arranged such that midpoints of adjacent sensors are separated by a distance of from 1 to 999 micrometer; and

    integrated circuits formed in the semiconductor chip such that an integrated circuit is assigned to each sensor of the sensor array to process the measurement signal produced by the assigned sensor, the integrated circuits in the semiconductor chip are each spatially formed under the sensor assigned thereto, and each integrated circuit comprisesa first switching transistor which supplies the working electrode of the assigned sensor with a first voltage when the first switching transistor is closed,a second switching transistor which supplies the working electrode of the assigned sensor with a second voltage, different from the first voltage, when the second switching transistor is closed,a voltage follower transistor that provides a third voltage that follows a voltage supplied to the voltage follower transistor by the working electrode of the assigned sensor, anda selection transistor which, together with the voltage follower transistor, electrically selects the assigned sensor by a column and a row of the sensor array.

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