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Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration

  • US 8,918,191 B2
  • Filed: 12/07/2011
  • Issued: 12/23/2014
  • Est. Priority Date: 12/07/2011
  • Status: Active Grant
First Claim
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1. A vagus nerve neurostimulator for treating chronic cardiac dysfunction with bounded titration, comprising:

  • a pulse generator, wherein the pulse generator generates a pulsed electrical signal comprising;

    a signal ON time;

    a signal OFF time;

    an output current;

    a signal frequency of approximately 10 Hz;

    a pulse width; and

    a duty cycle defined by dividing the signal ON time by the sum of the signal ON time and signal OFF time;

    a therapy lead;

    an electrode communicatively coupled to the pulse generator via the therapy lead, wherein the electrical signal is applied to a vagus nerve via the electrode to propagate action potentials in both afferent and efferent directions along the vagus nerve; and

    a leadless heart rate sensor configured to sense and record a patient'"'"'s heart rate in response to the pulsed electrical signal, wherein the pulse generator is configured to alter the pulsed electrical signal in response to the sensed heart rate falling outside of a stored predetermined range of acceptable heart rates.

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