Medical device
First Claim
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1. A method for treating a bifurcation or trifurcation aneurysm occurring on a first artery, the first artery and a second artery joining to a third artery, the method comprising:
- inserting a medical device such that it is at least partially located in the first artery and is at least partially located in the third artery;
expanding the medical device from a first position to a second position, said medical device is expanded radially outwardly to the second position such that the exterior surface of said medical device engages with the inner surface of the first and third arteries so as to maintain a fluid pathway through said arteries; and
positioning the medical device such that a membrane of the medical device is located against an aneurysm neck of the aneurysm to obstruct blood circulation to the aneurysm when the medical device is expanded to the second position, and at least a portion of the membrane is secured to the medical device to maintain the position of the membrane relative to the medical device when expanded to the second position;
wherein the membrane is permeable and porous, the size of the pores of the membrane and the ratio of the material surface area of the membrane being such that blood supply to perforators and/or microscopic branches of main brain arteries is permitted to improve healing of the first artery but blood supply to the aneurysm is reduced.
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Abstract
A method for treating an aneurysm can include inserting a medical device partially in a first artery and partially in a third artery. The device can be expanded radially outwardly from a first position to a second position to engage an inner surface of the first artery and an inner surface of the third artery, so as to maintain a fluid pathway through said arteries. Further, the device can be positioned such that, when the device is in the second position, a porous membrane of the device is located at a neck of the aneurysm.
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Citations
20 Claims
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1. A method for treating a bifurcation or trifurcation aneurysm occurring on a first artery, the first artery and a second artery joining to a third artery, the method comprising:
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inserting a medical device such that it is at least partially located in the first artery and is at least partially located in the third artery; expanding the medical device from a first position to a second position, said medical device is expanded radially outwardly to the second position such that the exterior surface of said medical device engages with the inner surface of the first and third arteries so as to maintain a fluid pathway through said arteries; and positioning the medical device such that a membrane of the medical device is located against an aneurysm neck of the aneurysm to obstruct blood circulation to the aneurysm when the medical device is expanded to the second position, and at least a portion of the membrane is secured to the medical device to maintain the position of the membrane relative to the medical device when expanded to the second position; wherein the membrane is permeable and porous, the size of the pores of the membrane and the ratio of the material surface area of the membrane being such that blood supply to perforators and/or microscopic branches of main brain arteries is permitted to improve healing of the first artery but blood supply to the aneurysm is reduced. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for treating a bifurcation or trifurcation aneurysm, in a patient, occurring at a first artery, the first artery and a second artery joining to a third artery, the method comprising:
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inserting a medical device partially in the first artery and partially in the third artery, the medical device comprising an expandable latticework frame having a plurality of struts that each define a radially outermost edge, a radially innermost edge, and an axial strut width, the radially outermost edge and the radially innermost edge defining a wall thickness therebetween, the medical device further comprising a porous membrane that extends around and between the plurality of struts, the membrane having a web portion that extends only in a central region, from a first strut of the plurality of struts to a second strut adjacent to the first strut, the first strut being spaced from the second strut at an interstitial spacing that is greater than the first or second strut width, the central region being (i) bounded radially between the radially outermost edges and the radially innermost edges of the first and second struts and (ii) bounded axially between the first strut and the second strut, the membrane web portion defining a web thickness that is less than the first or second strut wall thickness; expanding the device radially outwardly from a first position to a second position such that, when the device is in the second position, a first region of an exterior surface of the device engages an inner surface of the first artery and a second region of the exterior surface of the device engages an inner surface of the third artery, so as to maintain a fluid pathway through said arteries; and positioning the device such that, when the device is in the second position, the porous membrane, secured to the device, is located at a neck of the aneurysm; wherein the membrane has a substantially uniform porosity over a length extending from a distal end of the membrane to a proximal end of the membrane, and a distance between adjacent pores of the membrane does not exceed 75 microns; and wherein, when the device is in the second position and the membrane is positioned at the neck of the aneurysm, the membrane is effective to;
(i) reduce blood supply into the aneurysm, and (ii) permit blood supply through pores of the membrane and into perforators and/or microscopic branches of the first artery so as not to inhibit blood supply functions of the perforators and/or microscopic branches. - View Dependent Claims (12, 13, 14, 15)
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16. A method for treating an aneurysm, in a patient, the method comprising:
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inserting a medical device in a first vessel, the medical device having attached therewith a porous membrane with a substantially uniform porosity, and an expandable latticework frame having a plurality of struts that each define an axial strut width, a radially outermost edge, a radially innermost edge, and a wall thickness defined between the radially outermost edge and the radially innermost edge, wherein the porous membrane extends around and between the plurality of struts, the membrane having a single sheet web portion that extends only in a central region, from a first strut of the plurality of struts to a second strut adjacent to the first strut, the first strut being spaced from the second strut at an interstitial spacing that is greater than the first or second strut width, the central region being (i) bounded radially between the radially outermost edges and the radially innermost edges of the first and second struts and (ii) bounded axially between the first strut and the second strut, the membrane web portion defining a web thickness that is less than the first or second strut wall thickness; positioning the device such that the device and membrane is located at a neck of the aneurysm; and expanding the device radially outwardly from a first position to a second position such that, when the device is in the second position, a distal region of an exterior surface of the device engages an inner surface of the first vessel distal to the aneurysm, a proximal region of the exterior surface of the device engages an inner surface of the first vessel proximal to the aneurysm; wherein, when the device is in the second position, the membrane comprises pores with a size between about 20 microns and about 100 microns and a distance between adjacent pores that is not larger than 100 microns, such that the membrane reduces blood flow into the aneurysm and permits blood supply to small branch vessels, branching from the first vessel, through the pores of the membrane so as not to inhibit blood supply functions of the small branch vessels. - View Dependent Claims (17, 18, 19, 20)
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Specification