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Methods and compositions for increasing arylsulfatase A activity in the CNS

  • US 8,920,801 B2
  • Filed: 02/28/2014
  • Issued: 12/30/2014
  • Est. Priority Date: 12/02/2011
  • Status: Active Grant
First Claim
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1. A fusion antibody comprising:

  • (a) an arylsulfatase A (ASA) monomer, and (b) a single-chain antibody;

    wherein the fusion antibody crosses the blood brain barrier (BBB).

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