Systems and methods for radiometrically measuring temperature during tissue ablation

• US 8,926,605 B2
• Filed: 02/07/2012
• Issued: 01/06/2015
• Est. Priority Date: 02/07/2012
• Status: Active Grant

• Current Assignee: Coral Sand Beach, LLC, Advanced Cardiac Therapeutics, Inc. (Medtronic Plc)
• Original Assignee: Advanced Cardiac Therapeutics, Inc. (Medtronic Plc), Meridian Medical Systems LLC
• Inventors: McCarthy, John, Lenihan, Timothy J., Kanowsky, Eric R., Allison, Robert C.
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US13/368,112
• Publication Number:
  US 20130204240A1
• Time in Patent Office: 1,064 Days
• Field of Search: 606/34
• US Class Current: 606/34
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/12 by passing a current through the tissue to be heated, e.g. high-frequency current
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/0007 Pyrometers
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00648 using more than one sensed parameter
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00708 switching the power on or off
• CPC Class Codes: A61B 2018/00714 Temperature
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/00898 Alarms or notifications created in response to an abnormal condition
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: A61B 5/318 : Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61N 7/022 : intracavitary

Abstract

The present invention provides systems and methods for radiometrically measuring temperature during ablation. An interface module includes a processor; a first input/output (I/O) port configured to receive digital radiometer and thermocouple signals from an integrated catheter tip (ICT) that includes a radiometer; a second I/O port configured to receive ablative energy from an electrosurgical generator; a temperature display; a patient relay in communication with the first and second I/O ports and the processor; and a computer-readable medium storing radiometer and thermocouple operation parameters and instructions for causing the processor to: calculate a temperature adjacent to the ICT based on the radiometer and thermocouple signals and the operation parameters, causing the temperature display to display the calculated temperature, and closing the patient relay so as to pass ablative energy received on the second I/O port to the first I/O port.

Claims

1. An ablation system for facilitating delivery of ablative energy to targeted tissue of a subject, comprising:

a catheter comprising a proximal end and a distal end;

an integrated catheter tip located along the distal end of the catheter, the integrated catheter tip comprising a radiometer, a radiofrequency electrode and a temperature-measurement device;

a generator for providing power to the radiofrequency electrode;

wherein the radiofrequency electrode is configured to emit energy, when energized by the generator, to the targeted tissue of the subject;

a non-transitory computer-readable medium configured to store operation parameters for the radiometer and the temperature-measurement device; and

a processor configured to calculate a temperature of the targeted tissue of the subject at a depth relative to a surface of the targeted tissue based on, at least, a signal generated by the radiometer, a signal generated by the temperature-measurement device and the operation parameters stored on the computer-readable medium.

2. The system of claim 1, further comprising a temperature display for displaying the calculated temperature of tissue.

3. The system of claim 1, further comprising a controller for selectively activating and deactivating the radiofrequency electrode.

4. The system of claim 1, wherein the integrated catheter tip additionally comprises at least one electrocardiogram electrode.

5. The system of claim 1, further comprising an irrigation system comprising a pump in fluid communication with a fluid passage of the catheter, wherein the irrigation system is configured to selectively deliver irrigation fluid through the fluid passage of the catheter and at least one irrigation fluid port of the integrated catheter tip in fluid communication with the fluid passage of the catheter during use.

6. The system of claim 1, wherein the processor is configured to deactivate the radiofrequency electrode when the calculated temperature exceeds a threshold high temperature level.

7. The system of claim 1, wherein the catheter is steerable.

8. The system of claim 1, wherein the integrated catheter tip comprises a generally tubular shape.

9. The system of claim 1, wherein the integrated catheter tip comprises a flat distal end.

10. The system of claim 1, wherein the operation parameters for the radiometer comprise a slope and an offset describing a temperature response of the radiometer, and wherein the operation parameters for the temperature-measurement device comprise a slope and an offset describing a temperature response of the temperature-measurement device.

11. An ablation system for facilitating delivery of ablative energy to targeted tissue of a subject, comprising:

a catheter comprising a proximal end and a distal end;

a catheter tip located along the distal end of the catheter, the catheter tip comprising an ablation member, a radiometer and a temperature-measurement device, the temperature-measurement device being configured to detect a temperature along the catheter tip;

wherein, when electrically activated, the ablation member is configured to emit energy to the targeted tissue of the subject; and

wherein the system is configured to communicate with a processor that based on, at least, a signal generated by the radiometer and a signal generated by the temperature-measurement device, calculates a temperature of the targeted tissue of the subject at a depth relative to a surface of the targeted tissue.

12. The system of claim 11, wherein the ablation member comprises one of a radiofrequency electrode, a microwave ablation member, a cryoablation member, and an ultrasound ablation member.

13. The system of claim 11, wherein the catheter is steerable.

14. The system of claim 11, wherein the catheter tip additionally comprises at least one electrocardiogram electrode.

15. The system of claim 11, wherein the catheter comprises a fluid passage extending at least partially from the proximal end to the distal end, the catheter tip comprising at least one irrigation fluid port, wherein the at least one irrigation fluid port is in fluid communication with the fluid passage of the catheter, and wherein the fluid passage of the catheter is configured to be placed in fluid communication with an irrigation pump, the irrigation pump being configured to selectively deliver irrigation fluid through the fluid passage of the catheter and through the at least one irrigation fluid port of the catheter tip.

16. An ablation system for facilitating delivery of ablative energy to targeted tissue of a subject, comprising:

a catheter, wherein the catheter comprises an ablation member and a temperature-measuring device configured to detect a temperature along a portion of the catheter; and

a radiometer;

wherein the ablation member is configured to emit energy to the targeted tissue of the subject, when activated;

wherein the system is configured to communicate with a processor that based on, at least, a signal generated by the radiometer and a signal generated by the temperature-measuring device, calculates a temperature of the targeted tissue of the subject at a depth relative to a surface of the targeted tissue.

17. The system of claim 16, wherein the ablation member comprises one of a radiofrequency electrode, a microwave ablation member, a cryoablation member and an ultrasound ablation member.

18. The system of claim 16, wherein the catheter is steerable.

19. The system of claim 16, wherein the catheter comprises at least one electrocardiogram electrode.

20. The system of claim 16, wherein the catheter comprises a fluid passage extending at least partially from the proximal end to the distal end, the catheter comprising at least one irrigation fluid port, wherein the at least one irrigation fluid port is in fluid communication with the fluid passage of the catheter, and wherein the fluid passage of the catheter is configured to be placed in fluid communication with an irrigation pump, the irrigation pump being configured to selectively deliver irrigation fluid through the fluid passage of the catheter and through the at least one irrigation fluid port of the catheter.