Methods and devices for occlusion of an atrial appendage

• US 8,926,635 B2
• Filed: 10/02/2009
• Issued: 01/06/2015
• Est. Priority Date: 06/18/2004
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Francischelli, David E., Briscoe, Roderick E., Leuer, Leonard H., Haeg, Daniel C., Daigle, Tom P., Kim, David, Stewart, Mark T., Olson, Andrew L., Cloutier, Patrick J., Smith, Christopher W., Hobday, Michael J., Kanayinkal, Tessy, Gubbin, Douglas H., Rothstein, Paul T., Cardinal, Joseph E., Foley, Jessica L., Plott, Christopher J.
• Primary Examiner(s): McEvoy, Thomas
• Assistant Examiner(s): SZPIRA, JULIE ANN
• Application Number:
  US12/572,846
• Publication Number:
  US 20100145361A1
• Time in Patent Office: 1,922 Days
• Field of Search: 606/139, 606/142, 606/144, 606/157
• US Class Current: 606/139
• CPC Class Codes: A61B 17/12 for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord specially adapted for vas deferens or fallopian tubes A61F6/20; materials for ligaturing blood vessels A61L17/00
• CPC Class Codes: A61B 17/12009 Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/12018 Elastic band ligators

Abstract

A novel occluder application and clip device for treatment of embolic stroke caused by atrial fibrillation uses multiple sutures in a non directional handle to affix the occlusion device to the applicator and manipulate the occluder from an open and receiving position to a closed and occluding position. The occluder is retained in place by a clamping means related to locks retainers, resilient material or otherwise. An actuator mechanism is used to manipulate the occluder to a locked or occluding position. The applicator with the occluder attached has a low profile and remote manipulations to allow the occluder to be delivered to the clamping location within a patient through a small incision or delivery port such as a trocar cannula or the like.

Claims

1. A system for occluding a left atrial appendage of a patient, the system comprising:

a ring occluder that can be positioned around the left atrial appendage; and

a ring applicator to position the ring occluder with respect to the left atrial appendage,

the ring applicator including a ring spreader with a spreader hinge coupled to a first end of an upper spreader jaw and to a first end of a lower spreader jaw, the upper and lower spreader jaws each terminating at a second end opposite the corresponding first end,

the ring occluder coupled to the lower spreader jaw and the upper spreader jaw such that an outer edge of the ring occluder is positioned between the lower spreader jaw and the upper spreader jaw,

the spreader hinge having a four-bar assembly and moving between an open position in which the ring occluder has a first diameter and a closed position in which the ring occluder has a second diameter, the first diameter being larger than the second diameter,

wherein the upper spreader jaw between the corresponding first and second ends is substantially parallel with the lower spreader jaw between the corresponding first and second ends in the open position and in the closed position.

2. The system of claim 1 wherein the ring occluder includes at least one of micro-sized glass beads, glass fibers, and metallic fibers.

3. The system of claim 1 wherein the ring occluder includes a biocompatible, elastomeric material.

4. The system of claim 1 wherein the ring occluder is covered by a material to promote tissue ingrowth and prevent slippage.

5. The system of claim 1 wherein the ring applicator includes a jaw actuator that controls the spreader hinge.

6. The system of claim 1 wherein the ring applicator includes a lumen for insertion of a retraction mechanism.

7. The system of claim 1 wherein the ring applicator includes a lumen for insertion of a viewing device.

8. The system of claim 5 wherein the jaw actuator includes a knob and a torque screw.

9. The system of claim 5 wherein the jaw actuator includes a handle and a trigger mechanism.

10. The system of claim 5 wherein at least one suture is coupled to the jaw actuator, the spreader hinge, and the ring occluder.

11. The system of claim 1 wherein the ring applicator includes a plurality of slots and a plurality of apertures through which a plurality of sutures are positioned.