Minimally invasive lung volume reduction devices, methods, and systems

• US 8,932,310 B2
• Filed: 09/14/2012
• Issued: 01/13/2015
• Est. Priority Date: 03/13/2006
• Status: Expired due to Fees

• Current Assignee: Ekos LLC (Boston Scientific Corporation)
• Original Assignee: PneumRx, Inc. (Boston Scientific Corporation)
• Inventors: Thompson, David, Aronson, Nathan, Wu, Patrick, Lehrberg, David, Mathis, Mark L., Boutillette, Michael, Vasquez, Jaime
• Primary Examiner(s): ANDERSON, GREGORY A
• Application Number:
  US13/620,005
• Publication Number:
  US 20130217956A1
• Time in Patent Office: 851 Days
• Field of Search: 623/23.65, 606/151, 606/157
• US Class Current: 606/157
• CPC Class Codes: A61B 1/044 for absorption imaging
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12131 characterised by the type of occluding device
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 6/485 involving fluorescence X-ray imaging
• CPC Class Codes: A61B 90/00 Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges protective face masks A41D13/11; surgeon's or patient's gowns or dresses A41D13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M1/00
• CPC Class Codes: A61B 90/02 Devices for expanding tissue, e.g. skin tissue implements for holding wounds open, surgical tractors A61B17/02; implantable mammary prosthesis A61F2/12; dilators A61M29/00
• CPC Class Codes: A61F 2002/043 : Bronchi
• CPC Class Codes: A61F 2002/046 : Tracheae
• CPC Class Codes: A61M 16/04 : Tracheal tubes catheters in general A61M25/00
• CPC Class Codes: A61M 16/0406 : implanted flow modifiers
• CPC Class Codes: A61M 16/0833 : T- or Y-type connectors, e.g. Y-piece
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2205/0266 : Shape memory materials
• CPC Class Codes: A61M 2205/32 : with radio-opaque indicia
• CPC Class Codes: A61M 37/0069 : Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027

Abstract

A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.

Claims

1. A lung volume reduction device comprising:

an implant adapted for delivery into an airway of a lung, the airway extending along an elongate natural pathway, the implant including an elongate body extending between a proximal end and a distal end, the elongate body having an undelivered configuration and a delivered configuration in which at least a portion of the elongate body is altered from the undelivered configuration,

wherein the elongate body of the implant is configured to deploy into the delivered configuration within the airway so as to move the elongate body and impart at least one bend in the airway such that the elongate natural pathway is directionally altered.

2. The device of claim 1, wherein distance between the proximal and distal ends of the elongate body is reduced in the delivered configuration as compared to the undelivered configuration.

3. The device of claim 1, wherein at least one curve is formed along the elongate body between the proximal and distal ends in the delivered configuration, the at least one curve defining the at least one bend in the airway.

4. The device of claim 3, wherein the at least one curve comprises a complete loop of the elongate body.

5. The device of claim 3, wherein the at least one curve comprises a partial loop of the elongate body.

6. The device of claim 1, wherein a plurality of curves is formed along the elongate body between the proximal and distal ends in the delivered configuration such that a plurality of respective bends are formed in the airway.

7. The device of claim 6, wherein the plurality of curves comprises coils.

8. The device of claim 6, wherein the plurality of curves bring the proximal and distal ends closer together.

9. The device of claim 6, wherein each of the plurality of curves are positioned in different planes.

10. The device of claim 1, wherein elongate body comprises at least one wire.

11. A method for applying tension to lung tissue comprising:

inserting an implant into an airway of a lung to apply tension on lung tissue outside the airway,

wherein the implant increases tortuosity of the airway,

wherein the implant forms at least one loop or bend to respectively impart at least one similarly shaped loop or similarly shaped bend in the airway.

12. The method of claim 11, wherein the implant alters the airway to such a degree that lung tissue outside the airway is pulled closer to the device.

13. The method of claim 11, wherein the implant is released from a constrained configuration.

14. The method of claim 13, wherein the implant moves via elastic recovery.

15. The method of claim 11, wherein the implant is inserted using a bronchoscope.

16. The method of claim 15, wherein the implant is delivered into the airway from a catheter within the bronchoscope.

17. The method of claim 11, wherein lung tissue is compressed within the at least one similarly shaped loop or similarly shaped bend in the airway.