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Nicotine immunonanotherapeutics

  • US 8,932,595 B2
  • Filed: 10/09/2009
  • Issued: 01/13/2015
  • Est. Priority Date: 10/12/2008
  • Status: Active Grant
First Claim
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1. A composition comprising:

  • (1) synthetic nanocarriers having at least one surface, wherein a first surface of the synthetic nanocarriers comprises an immunofeature surface comprising a plurality of nicotine moieties,wherein the immunofeature surface binds to antigen presenting cells with high avidity and low affinity as compared to an antibody that is specific for an antigen presenting cell-expressed surface antigen; and

    (2) a pharmaceutically acceptable excipient.

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