Pharmaceutical products from fungal strains

• US 8,932,602 B2
• Filed: 08/11/2011
• Issued: 01/13/2015
• Est. Priority Date: 08/11/2010
• Status: Active Grant

• Current Assignee: Menon Renewable Products, Inc. (Menon & Associates, Inc.)
• Original Assignee: Menon Renewable Products, Inc. (Menon & Associates, Inc.)
• Inventors: Menon, Suresh M., Orchard, Samantha S., Badger, Jessica, Guidi, Sara, Newman, David, Sircar, Jagadish C., Alisala, Kashinatham
• Primary Examiner(s): Tate, Chris R
• Assistant Examiner(s): White, Douglas F
• Application Number:
  US13/816,128
• Publication Number:
  US 20130149333A1
• Time in Patent Office: 1,251 Days
• Field of Search: None
• US Class Current: 424/195.15
• CPC Class Codes: A01N 63/36 Penicillium
• CPC Class Codes: A61K 36/062 Ascomycota
• CPC Class Codes: C12N 1/145 Fungal isolates
• CPC Class Codes: C12P 1/02 by using fungi
• CPC Class Codes: C12R 2001/80 Penicillium

Abstract

Disclosed herein are compositions comprising an isolated cellulose degrading fungus and pharmaceutical substances produced by the fungus.

Claims

1. A process for producing an inhibitory substance comprising:

a) incubating a cellulose degrading fungus of the genus Penicillium in a liquid medium for a sufficient time for production of an inhibitory substance by said fungus; and

b) separating said fungus from said liquid medium, thereby producing a harvested fungus and a conditioned liquid medium, wherein said conditioned liquid medium comprises said inhibitory substance produced by said fungus;

wherein said cellulose degrading fungus comprises a species being the same as NRRL deposit Accession No;

50410.

2. The process of claim 1, wherein said inhibitory substance is an antimicrobial substance.

3. The process of claim 2, wherein said inhibitory substance is a bacteriostatic agent.

4. The process of claim 2, wherein said inhibitory substance is a bacteriocidal agent.

5. The process of claim 1, further comprising:

c) extracting said inhibitory substance from said conditioned medium.