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Glucagon-like peptide-2 analogs

  • US 8,933,039 B2
  • Filed: 06/15/2010
  • Issued: 01/13/2015
  • Est. Priority Date: 04/14/1995
  • Status: Expired due to Fees
First Claim
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1. An intestinotrophic GLP-2 analog, comprising SEQ ID NO:

  • 2, whereinposition 2 of SEQ ID NO;

    2 consists of an amino acid other than Ala,positions 5-9, 11-18, and 21-23 of SEQ ID NO;

    2 are unmodified,position 1 of SEQ ID NO;

    2 optionally consists of an amino acid other than His;

    position 3 of SEQ ID NO;

    2 optionally consists of an amino acid other than Asp;

    position 4 of SEQ ID NO;

    2 optionally consists of an amino acid other than Gly;

    position 10 of SEQ ID NO;

    2 optionally consists of an amino acid other than Met;

    position 19 of SEQ ID NO;

    2 optionally consists of an amino acid other than Ala;

    position 20 of SEQ ID NO;

    2 optionally consists of an amino acid other than Arg; and

    position 24 of SEQ ID NO;

    2 optionally consists of an amino acid other than Asn.

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