Spinal cord stimulation to treat pain

• US 8,934,981 B2
• Filed: 07/16/2012
• Issued: 01/13/2015
• Est. Priority Date: 03/15/2007
• Status: Active Grant

• Current Assignee: Dirk D.E. Ridder
• Original Assignee: Dirk D.E. Ridder
• Inventors: De Ridder, Dirk
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): Bays, Pamela M
• Application Number:
  US13/550,196
• Publication Number:
  US 20120283797A1
• Time in Patent Office: 911 Days
• Field of Search: 607/2, 607/3, 607/30, 607/31, 607/45, 607/46, 607/117
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36153 Voltage A61N1/3616 takes precedence
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A system and method for treating pain without paresthesia by spinal cord stimulation. In one embodiment, a method comprises storing one or more operating parameters for a high frequency stimulus having a plurality of pulses, wherein the high frequency stimulus comprises at least respective pairs of pulses that have an inter-pulse separation within a range of 0.1 milliseconds to 10 milliseconds; and applying generated electrical pulses of the high frequency stimulus to the patient through a set of one or more electrodes of an electrical lead implanted within epidural space of the patient to treat the chronic pain of the patient without causing paresthesia in the patient.

Claims

1. A method of treating chronic pain, including lower back pain and leg pain, in a patient with spinal cord stimulation, the method comprising:

storing one or more operating parameters for a high frequency stimulus having a plurality of pulses, wherein the high frequency stimulus comprises at least respective pairs of pulses that have a pulse separation within a range of 0.1 milliseconds to 1.0 milliseconds;

operating a pulse generator to generate electrical pulses of the high frequency stimulus; and

applying the generated electrical pulses of the high frequency stimulus to the patient through a set of one or more electrodes of an electrical lead implanted within epidural space of the patient to treat the lower back pain and leg pain of the patient without causing paresthesia in the lower back or legs of the patient where resulting pain relief occurs during application of the pulses of the high frequency stimulus.

2. The method of claim 1 wherein the applying treats chronic pain resulting from failed back surgery syndrome.

3. The method of claim 1 further comprising:

pseudo-randomly varying a pulse repetition frequency for the pulses within the high frequency stimulus.

4. The method of claim 1 further comprising:

applying one or more quiescent intervals within the high frequency stimulus.

5. The method of claim 4 wherein each quiescent interval is between approximately 10 milliseconds to 300 milliseconds.

6. The method of claim 1 wherein an amplitude of pulses within a plurality of groups of pulses within the high frequency stimulus increases within each respective group.

7. The method of claim 6 wherein each group within the plurality of group of pulses is terminated by a charge balancing pulse that has a pulse width greater than a pulse width employed for other pulses of the respective group.

8. The method of claim 1 wherein the set of electrodes are disposed within at least one vertebral level selected from the listing consisting of:

T8, T9, T10, T11, and T12.

9. A method of treating chronic pain in a patient with spinal cord stimulation, the method comprising:

storing one or more operating parameters for a burst stimulus having a plurality of groups of pulses, wherein (i) the burst stimulus is substantially quiescent between each group of the plurality of groups of pulses with a quiescent interval of at least 1 millisecond and less than about 5 seconds and (ii) the burst stimulus comprises respective groups of pulses with at least one pulse that is followed by another pulse within 0.1 to 10.0 milliseconds;

operating a pulse generator to generate electrical pulses of the burst stimulus; and

applying the burst stimulus to the patient through one or more electrodes of an electrical lead implanted within epidural space of the patient to treat the chronic pain of the patient without causing paresthesia in the patient.

10. The method of claim 9 wherein the applying treats pain resulting from failed back surgery syndrome.

11. The method of claim 9 further comprising:

pseudo-randomly varying a pulse repetition frequency for the plurality of groups of pulses within the burst stimulus.

12. The method of claim 9 further comprising:

pseudo-randomly varying the quiescent interval for the plurality of groups of pulses within the burst stimulus.

13. The method of claim 9 wherein the quiescent interval is between approximately 10 milliseconds to 300 milliseconds.

14. The method of claim 9 wherein an amplitude of pulses within the plurality of groups of pulses increases within each respective group.

15. The method of claim 9 wherein each group within the plurality of group of pulses is terminated by a charge balancing pulse that has a pulse width greater than a pulse width employed for other pulses of the respective group.

16. The method of claim 9 wherein the groups of pulses within the burst stimulus repeat at approximately 40 Hz.

17. The method of claim 9 wherein the epidural space of the patient is further defined as thoracic epidural space of T8, T9, T10, T11, T12 or a combination thereof.