Drug delivery pump drive using linear piezoelectric motor

• US 8,936,574 B2
• Filed: 01/04/2013
• Issued: 01/20/2015
• Est. Priority Date: 10/18/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Wiegel, Christopher, DePolo, Marco, Roe, Steven
• Primary Examiner(s): MEDWAY, SCOTT J
• Application Number:
  US13/734,475
• Publication Number:
  US 20130123749A1
• Time in Patent Office: 746 Days
• Field of Search: 604/155, 604/107, 604/108, 604/209, 604/156, 604/165.04, 604/211, 604/31, 604/134, 604/151, 604/256, 310/311, 310/328
• US Class Current: 604/155
• CPC Class Codes: A61M 2205/8212 with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: F04B 17/003 driven by piezoelectric means F04B43/046 and F04B43/095 take precedence
• CPC Class Codes: F04B 43/046 with piezoelectric drive
• CPC Class Codes: F04B 43/095 Piezoelectric drive

Abstract

A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump.

Claims

1. A drive system used to dispense a liquid drug from a drug container having a piston, said drive system comprising:

a lead screw having a rotational axis and operably connected to the piston;

a ratchet wheel provided along the rotational axis and operably connected to the lead screw to move the lead screw;

a piezoelectric motor having a shaft, a first nut engaging the shaft, and piezoelectric elements configured to produce reciprocating linear motion of the shaft relative to the first nut adjacent the rotational axis, wherein the shaft of the piezoelectric motor is situated perpendicular to the rotational axis and is connected to a rocker; and

a pawl operably connected to the shaft and engaging the ratchet wheel such that the reciprocating linear motion of the shaft is converted into unidirectional rotary motion of the ratcheted wheel about the rotational axis which moves the lead screw and advances the piston to dispense the liquid drug from the drug container.

2. The drive system according to claim 1, wherein the lead screw is fixed to the ratchet wheel and operably connected to the piston via a second nut.

3. The drive system according to claim 1, wherein the lead screw is fixed to the ratchet wheel and operably connected to the piston via a second nut, the second nut having a key portion mounted slidably in a keyway of the drive system such that the second nut is able to translate relative to the lead screw but not rotate.

4. The drive system according to claim 1, wherein the ratchet wheel is mounted rotatably about the lead screw, and the drive system further comprises a retainer arranged to constrain the ratchet wheel from translating up the rotational axis as the ratchet wheel rotates about the lead screw.

5. The drive system according to claim 1, wherein the ratchet wheel is mounted rotatably about the lead screw, and the drive system further comprises a retainer arranged to constrain the ratchet wheel from translating up the rotational axis as the ratchet wheel rotates about the lead screw, wherein the retainer provides a through bore into which the lead screw is slidably accommodated and has a detent portion provided inside the through bore which rides in a longitudinally extending slot provided in the lead screw.

6. The drive system according to claim 1, wherein the ratchet wheel is mounted slidably about the lead screw, a second nut receives the lead screw and causes the lead screw to translate as it is rotated by the ratchet wheel and the lead screw is operably connected to the piston, wherein the second nut is fixed.

7. The drive system according to claim 1, wherein the pawl has an end fixed to the rocker.

8. The drive system according to claim 1, wherein the pawl has an end fixed to the rocker, wherein the lead screw is fixed to the ratchet wheel and operably connected to the piston via a second nut, the second nut having a key portion mounted slidably in a keyway of the drive system such that the second nut is able to translate relative to the lead screw but not rotate and the second nut is operably connected to the piston.

9. The drive system according to claim 1, wherein the pawl has an end fixed to the rocker, wherein the ratchet wheel is mounted rotatably about the lead screw, the drive system further comprises a retainer arranged to constrain the ratchet wheel from translating up the rotational axis as the ratchet wheel rotates about the lead screw, wherein the retainer provides a through bore into which the lead screw is slidably accommodated and has a detent portion provided inside the through bore which rides in a longitudinally extending slot provided in the lead screw and the lead screw is operably attached to the piston.

10. The drive system according to claim 1, wherein the pawl has an end fixed to the rocker, wherein the ratchet wheel is mounted slidably about the lead screw, a second nut receives the lead screw and causes the lead screw to translate as it is rotated by the ratchet wheel, and the lead screw is operably connected to the piston, wherein the second nut is fixed.

11. The drive system according to claim 1, wherein the drive system is provided in a miniature drug delivery pump.

12. The drive system according to claim 11, wherein the drive system is provided in the miniature drug delivery pump such that a portion of the piston is visible through a sealed window provided by the miniature drug delivery pump.

13. A method for dispensing a liquid drug from a drug container having a piston, said method comprising:

providing a lead screw having a rotational axis and operably connected to the piston;

providing a ratchet wheel along the rotational axis and operably connected to the lead screw to move the lead screw;

providing a piezoelectric motor having a shaft, a first nut engaging the shaft, and piezoelectric elements configured to produce reciprocating linear motion of the shaft relative to the first nut adjacent the rotational axis, wherein the shaft of the piezoelectric motor is situated perpendicular to the rotational axis and is connected to a rocker; and

providing a pawl operably connected to the shaft and engaging the ratchet wheel such that the reciprocating linear motion of the shaft is converted into unidirectional rotary motion of the ratcheted wheel about the rotational axis which moves the lead screw, wherein moving the lead screw advances the piston dispensing the liquid drug from the drug container.

14. The method according to claim 13, further comprising linearly reciprocating the shaft of the piezoelectric motor perpendicular to the rotational axis, which moves the lead screw and advances the piston to dispense the liquid drug from the drug container.

15. The method according to claim 13, further comprising providing a second nut mounted rotatably about the lead screw and engaging the piston, wherein the ratchet wheel and lead screw are fixed together, linearly reciprocating the shaft of the piezoelectric motor perpendicular to the rotational axis which translates the second nut relative to the lead screw and advances the piston to dispense the liquid drug from the drug container.

16. The method according to claim 13, wherein the ratchet wheel is mounted rotatably about the lead screw and the lead screw engages the piston, the method further comprising linearly reciprocating the shaft of the piezoelectric motor perpendicular to the rotational axis which translates the lead screw relative to the ratchet wheel and advances the piston to dispense the liquid drug from the drug container.

17. The method according to claim 13, wherein the ratchet wheel is mounted slidably about the lead screw and the lead screw engages the piston, the method further comprises linearly reciprocating the shaft of the piezoelectric motor perpendicular to the rotational axis which translates and rotates the lead screw relative to the ratchet wheel and advances the piston to dispense the liquid drug from the drug container.