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Methods of loading a hollow stent with a drug or drug formulation

  • US 8,936,827 B2
  • Filed: 02/25/2011
  • Issued: 01/20/2015
  • Est. Priority Date: 02/25/2011
  • Status: Active Grant
First Claim
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1. A method of loading a composition into a structural element of a stent, comprising;

  • providing a stent having a structural element or providing a structural element that is to be used in forming a stent, the structural element defined by a lumen and least one opening to access the lumen;

    heating the structural element to a temperature of about 30°

    C. to about 60°

    C.;

    after heating the structural element, injecting a composition in a fluid state into the opening to load the lumen with the composition, wherein the composition comprises a therapeutic agent, and wherein the composition is in a solid state or a semi-solid state has at a temperature of 30°

    C. and at one atmosphere; and

    maintaining the structural element between about 30°

    C. to about 60°

    C. until the injection is completed.

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