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Silicone hydrogels comprising desirable water content and oxygen permeability

  • US 8,937,111 B2
  • Filed: 12/19/2012
  • Issued: 01/20/2015
  • Est. Priority Date: 12/23/2011
  • Status: Active Grant
First Claim
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1. A silicone hydrogel comprising a water content of at least about 50% and an oxygen permeability of at least about 80 barrers wherein said silicone hydrogel is formed from a reaction mixture comprisingabout 37 to about 75 wt % of at least one slow-reacting hydrophilic monomer having a slow-reacting hydrophilic monomer kinetic half life;

  • at least one silicone-containing component having a silicone-containing component kinetic half life, which may be optionally substituted with at least one hydroxyl containing group;

    at least one hydroxyl-containing component selected from said silicone-containing components substituted with at least one hydroxyl group, at least one hydroxyalkyl monomer, and mixtures thereof,wherein ratio of said slow-reacting hydrophilic component half life to said silicone-containing component half life is at least 2, said reaction mixture comprising between 9 and 14 wt % silicon from all components and less than 15 wt % TRIS and wherein all reactive components other than said slow-reacting hydrophilic monomer and said silicone containing components are ancillary components and are present in the reaction mixture are present in an amount between about 11 and about 92 mmol/100 g reactive components.

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