Multidepth tissue oximeter
First Claim
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1. A method comprising:
- providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors,the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line,the first, second, and third lines are parallel to each other, andthe second line is between the first and the third lines;
using the first and second structures of the probe, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a three-dimensional region and at the first depth, this region extends in directions parallel and transverse to the second line;
using the first and third structures of the probe, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a three-dimensional region and at the second depth, this region extends in directions parallel and transverse to the third line;
displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and
displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen,wherein the probe comprises a first light shading film, associated with the second structures, allowing a first spectrum of light to pass through to the second structures, anda second light shading film, associated with the third structures, allowing a second spectrum of light to pass through to the third structures, wherein the first spectrum is different from the second spectrum.
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Abstract
An oximeter measures oxygen saturation for two or more different tissue depths and shows these results on a screen. A probe of the oximeter has multiple different distances between source and detector sensors. One probe implementation has fixed sensor positions. Other implementations include sensors on a moveable platform or openings to accept sensors, which allow a user to vary a distance between sensors.
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Citations
62 Claims
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1. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using the first and second structures of the probe, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a three-dimensional region and at the first depth, this region extends in directions parallel and transverse to the second line; using the first and third structures of the probe, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a three-dimensional region and at the second depth, this region extends in directions parallel and transverse to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a first light shading film, associated with the second structures, allowing a first spectrum of light to pass through to the second structures, and a second light shading film, associated with the third structures, allowing a second spectrum of light to pass through to the third structures, wherein the first spectrum is different from the second spectrum. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using the first and second structures of the probe, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a three-dimensional region and at the first depth, this region extends in directions parallel and transverse to the second line; using the first and third structures of the probe, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a three-dimensional region and at the second depth, this region extends in directions parallel and transverse to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a first light shading film, associated with the second structures, allowing a first spectrum of light to pass through to the second structures, and a second light shading film, associated with the third structures, allowing a second spectrum of light to pass through to the third structures, wherein the first spectrum is different from the second spectrum, the probe comprises a plurality of fourth structures, wherein the fourth structures comprise detectors and are arranged in a fourth line, and the probe comprises a plurality of fifth structures, wherein the fifth structures comprise detectors, the fifth structures are arranged in a fifth line, and the fourth and fifth lines are parallel to the first, second, and third lines.
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17. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using at least one processor, electronically selecting the first and second structures of the probe to send and receive a first combination of light signals; based on the first combination of light signals, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a cross section extending in a direction parallel to the second line; using at least one processor, electronically selecting the first and third structures of the probe to send and receive a second combination of light signals; using the second combination of light signals, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a cross section extending in a direction parallel to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a light shading film, coupled to the probe, positioned below the second structures such that light received at the second structures passes through the light shading film, and light received at the third structures does not pass through the light shading film. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using at least one processor, electronically selecting the first and second structures of the probe to send and receive a first combination of light signals; based on the first combination of light signals, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a cross section extending in a direction parallel to the second line; using at least one processor, electronically selecting the first and third structures of the probe to send and receive a second combination of light signals; using the second combination of light signals, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a cross section extending in a direction parallel to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a light shading film, coupled to the probe, positioned below the second structures such that light received at the second structures passes through the light shading film, and light received at the third structures does not pass through the light shading film, a structure of the probe retains the first and second structures at fixed positions, such that the first line and second line are at a first fixed distance from each other, a structure of the probe retains the first and third structures at fixed positions, such that the first line and third line are at a second fixed distance from each other, and the second fixed distance is greater than the first fixed distance, and upon moving the probe from one location to another, the structure of the probe maintains the first and second fixed distances without needing to reposition the first, second, and third structures separately.
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30. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using at least one processor, electronically selecting the first and second structures of the probe to send and receive a first combination of light signals; based on the first combination of light signals, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a cross section extending in a direction parallel to the second line; using at least one processor, electronically selecting the first and third structures of the probe to send and receive a second combination of light signals; using the second combination of light signals, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a cross section extending in a direction parallel to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a light shading film, coupled to the probe, positioned below the second structures such that light received at the second structures passes through the light shading film, and light received at the third structures does not pass through the light shading film, the probe comprises a plurality of fourth structures, wherein the fourth structures comprise detectors and are arranged in a fourth line, and the probe comprises a plurality of fifth structures, wherein the fifth structures comprise detectors, the fifth structures are arranged in a fifth line, and the fourth and fifth lines are parallel to the first, second, and third lines.
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31. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using the first and second structures of the probe, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a three-dimensional region and at the first depth, this region extends in directions parallel and transverse to the second line; using the first and third structures of the probe, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a three-dimensional region and at the second depth, this region extends in directions parallel and transverse to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a first light shading film, associated with the second structures, allowing a first spectrum of light to pass through to the second structures, and a second light shading film, associated with the third structures, allowing a second spectrum of light to pass through to the third structures, wherein the first spectrum is different from the second spectrum, a structure of the probe retains the first and second structures at fixed positions, such that the first line and second line are at a first fixed distance from each other, a structure of the probe retains the first and third structures at fixed positions, such that the first line and third line are at a second fixed distance from each other, and the second fixed distance is greater than the first fixed distance, and upon moving the probe from one location to another, the structure of the probe maintains the first and second fixed distances without needing to reposition the first, second, and third structures separately.
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32. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using the first and second structures of the probe, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a three-dimensional region and at the first depth, this region extends in directions parallel and transverse to the second line; using the first and third structures of the probe, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a three-dimensional region and at the second depth, this region extends in directions parallel and transverse to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a light shading film, coupled to the probe, positioned below the second structures such that light received at the second structures passes through the light shading film, and light received at the third structures does not pass through the light shading film. - View Dependent Claims (33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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46. A method comprising:
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providing a probe comprising a plurality of first structures, a plurality of second structures, and a plurality of third structures, wherein the first structures comprise sources, and the second and third structures comprise detectors, the first structures are arranged in a first line, the second structures are arranged in a second line, and the third structures are arranged in a third line, the first, second, and third lines are parallel to each other, and the second line is between the first and the third lines; using at least one processor, electronically selecting the first and second structures of the probe to send and receive a first combination of light signals; based on the first combination of light signals, calculating a first oxygen saturation measurement for a first tissue at a first depth below a tissue surface, wherein the first tissue comprises a cross section extending in a direction parallel to the second line; using at least one processor, electronically selecting the first and third structures of the probe to send and receive a second combination of light signals; using the second combination of light signals, calculating a second oxygen saturation measurement for a second tissue at a second depth below the tissue surface, wherein the second depth is beneath the first depth, and the second tissue comprises a cross section extending in a direction parallel to the third line; displaying a first value indicative of the first oxygen saturation measurement at a first position on a screen; and displaying a second value indicative of the second oxygen saturation measurement at a second position on the screen, wherein the probe comprises a first light shading film, associated with the second structures, allowing a first spectrum of light to pass through to the second structures, and a second light shading film, associated with the third structures, allowing a second spectrum of light to pass through to the third structures, wherein the first spectrum is different from the second spectrum. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62)
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Specification