Leadless implantable intravascular electrophysiologic device for neurologic/cardiovascular sensing and stimulation

• US 8,938,300 B2
• Filed: 05/04/2005
• Issued: 01/20/2015
• Est. Priority Date: 05/04/2004
• Status: Active Grant

• Current Assignee: University of Rochester
• Original Assignee: University of Rochester
• Inventors: Rosero, Spencer
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US11/579,529
• Publication Number:
  US 20080119911A1
• Time in Patent Office: 3,548 Days
• Field of Search: 607/2, 607/9, 607/36, 607/62, 607/45
• US Class Current: 607/45
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/362 Heart stimulators heart defibrillators A61N1/39
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/37516 Intravascular implants
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

A leadless intravascular sensor (100, 200) uses the body tissue as a communication medium. The implantable intravascular device has a tubular stent-like structure (102) for intravascular fixation with embedded microcircuits to allow bipolar and unipolar sensing of cardiac and neurologic electrical activity, sensing of other physiologic signals, local electrical stimulation (cardiac pacing and defibrillation; neurologic stimulation and seizure therapy) as well as the ability to communicate with other implanted and non implanted devices via radio frequency and/or optical communication and/or analog signal communication using body tissue as the conducting medium. The device can also be used in the extravascular or perivascular space. In this form, it has an open/flexible ring that can be adjusted, or self-adjusts to provide no pressure or required contact around the vessel or target region.

Claims

1. An implantable device comprising:

a body generally forming an elongated tubular shape and adapted to being implanted in each of an intravascular, extravascular and perivascular space within patient'"'"'s body;

an electronic component secured to the body having at least one sensor for sensing electrical or physiological conditions within the patient'"'"'s body and having at least one electrode for stimulation of tissue at or near the location of implantation wherein the electronic component is configured to output a stimulation through the at least one electrode in response to the sensed electrical air physiological conditions;

a wireless communication component secured to the body for communicating to and from the device information about the sensed electrical or physiological conditions from the sensor to a second implantable device of similar construction, a controller adapted to coordinate the response to the sensed electrical or physiological conditions with the electronic component and the second device; and

an induction coil integral to at least a portion of the body for providing power to the electronic component;

wherein the controller is configured to communicate with the electronic component and the second device to;

(i) sense with said sensor at a first location where a physiologic stimulus is present and sense at a second location associated with said second device where the physiologic stimulus is absent;

(ii) apply a first stimulation to said electrode at said first location to treat the physiologic stimulus; and

(iii) apply a second stimulation by way of the second implantable device at said second location to prevent the physiologic stimulus from reaching the second location;

wherein the physiologic stimulus is a seizure.

2. The device of claim 1, wherein said wireless communication component further comprises a wireless transmitter for wireless communication.

3. The device of claim 1, wherein said body comprises a support structure having a pattern.

4. The device of claim 3, wherein the induction coil has a pattern that follows the support structure pattern.

5. The device of claim 1, wherein said device is adapted to being secured at a target intravascular site.

6. The device of claim 1, wherein said device is expandable.

7. The device of claim 6, wherein said device is adapted to be delivered intravascularly to a target site and expanded at the target site to be fixed in position at the target site.

8. The device of claim 1, wherein the device is leadless.

9. The device of claim 1, wherein the body has a stent-like structure.

10. The device of claim 1, wherein said device is adapted to being networked with other extravascular or intravascular devices.

11. The device of claim 1, wherein the seizure is an epileptic seizure.