Multi-lumen cannula

• US 8,939,882 B2
• Filed: 07/30/2012
• Issued: 01/27/2015
• Est. Priority Date: 05/20/2009
• Status: Active Grant

• Current Assignee: TC1 LLC (Abbott Laboratories Incorporated)
• Original Assignee: Thoratec LLC
• Inventors: Reichenbach, Steven H., Law, Yu Fai
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Wu, Eugene
• Application Number:
  US13/561,197
• Publication Number:
  US 20120296152A1
• Time in Patent Office: 911 Days
• Field of Search: 600/16, 604/4.01, 604/6.11, 623/3.1
• US Class Current: 600/16
• CPC Class Codes: A61M 1/3653 Interfaces between patient blood circulation and extra-corporal blood circuit
• CPC Class Codes: A61M 1/3659 Cannulae pertaining to extracorporeal circulation
• CPC Class Codes: A61M 2025/0035 characterized by a variable lumen cross-section by means of a resilient flexible septum or outer wall
• CPC Class Codes: A61M 25/0023 by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/0032 characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
• CPC Class Codes: A61M 60/117 for assisting the heart, e.g. transcutaneous or external ventricular assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/20 Type thereof
• CPC Class Codes: A61M 60/857 Implantable blood tubes
• CPC Class Codes: A61M 60/859 Connections therefor

Abstract

This document relates to methods and materials for providing blood flow for a blood pump recipient. For example, cannulae that can be connected to the circulatory system of a mammal and can be used in conjunction with a blood pump (e.g., an assist device) are provided.

Claims

1. A method for implanting a cannula into a cardiovascular system, the method comprising:

creating a single puncture site into the cardiovascular system for receiving the cannula;

inserting the cannula through the puncture site such that a distal end of a first lumen of the cannula and a distal end of a second lumen of the cannula pass through the puncture site into the cardiovascular system, the second lumen having a non-circular cross-sectional shape extending between a first end portion and a second end portion, the first and second end portions having rounded corners each with a radius greater than about ten percent of the radius of the largest circle that can be inscribed within the second lumen and less than the radius of the largest circle that can be inscribed within the second lumen;

positioning the distal end of the first lumen of the cannula within a first portion of the cardiovascular system; and

positioning the distal end of the second lumen of the cannula within a second portion of the cardiovascular system, such that in use blood is received in the cannula from the distal end of the second lumen and blood is pumped from the cannula through the distal end of the first lumen having a cross-sectional area smaller than the cross-sectional area of the second lumen.

2. The method of claim 1, wherein the distal end of the second lumen is positioned in the left ventricle or the left atrium, and wherein the distal end of the first lumen is positioned in the aorta.

3. The method of claim 2, wherein the single puncture site is at the apex of the heart.

4. The method of claim 1, further comprising connecting a blood pump to a proximal region of the cannula, the proximal region of the cannula comprising proximal ends of the first and second lumens.

5. The method of claim 4, further comprising placing the blood pump in the abdominal cavity.

6. The method of claim 1, wherein the single puncture site is into the heart, the method further comprising connecting the cannula to the heart by anastomosis.

7. The method of claim 6, wherein once the cannula is positioned at a desired configuration relative to the heart, the cannula is secured to the myocardium using sutures.

8. The method of claim 1, wherein inserting the cannula comprises inserting the cannula through a septum of the heart.

9. The method of claim 8, wherein the distal end of the second lumen is positioned in the left ventricle or the left atrium, and wherein the distal end of the first lumen is positioned in the aorta.

10. The method of claim 1, wherein the distal end of the second lumen is positioned in the right ventricle or the right atrium, and wherein the distal end of the first is positioned in the pulmonary artery.

11. The method of claim 1, wherein creating the single puncture site into the cardiovascular system is accomplished by cannulation, incision, or excision of the myocardium.

12. The method of claim 1, wherein the distal end of the second lumen is positioned in the heart, and wherein the distal end of the first lumen is positioned in a blood vessel.

13. The method of claim 1, wherein the cross-sectional area of the first lumen and the second lumen is about 93% of the cross-sectional area of the cannula.

14. The method of claim 1, wherein the cross-sectional areas of the first lumen and the second lumen are substantially maintained during use.

15. The method of claim 1, wherein the distal end of the first lumen is sufficiently flexible to permit manipulation within the cardiovascular system, and wherein the distal end of the second lumen is rigid.

16. The method of claim 1, wherein the cross-sectional shape of the second lumen comprises a reniform shape.

17. A cannula for use with a blood pump, the cannula comprising:

a housing having a proximal region, a distal region, and an intermediate region located between the proximal and distal regions, wherein the housing defines a first lumen and a second lumen,

wherein the first lumen comprises;

(a) a proximal end located at or near the proximal region of the housing and adapted to engage the blood pump, and

(b) a distal end located at or near the distal region of the housing and adapted to be positioned within a cardiovascular system,

wherein the second lumen comprises;

(a) a proximal end located at or near the proximal region of the housing and adapted to engage the blood pump, and

(b) a distal end located at or near the intermediate region of the housing and adapted to be positioned within the cardiovascular system,

wherein one of the first and second lumens has a cross-sectional shape extending between a first end portion and a second end portion, the first and second end portions having rounded corners each with a radius greater than about ten percent of the radius of the largest circle that can be inscribed within the one of the first and second lumens and less than the radius of the largest circle that can be inscribed within the one of the first and second lumens, such lumen with rounded corners being off-set from the geometric center of the other lumen.

18. The cannula of claim 17, wherein the one of the first and second lumens comprises the second lumen.

19. The cannula of claim 18, wherein the cross-sectional shape of the second lumen comprises a reniform shape.

20. The cannula of claim 17, wherein the distal end of the first lumen is sufficiently flexible to permit manipulation within the cardiovascular system, and wherein the distal end of the second lumen is rigid.

21. The cannula of claim 17, wherein the first and second lumens are separated by a septum having a concave surface on one side to define a portion of the first lumen and a convex surface on an opposite side to define a portion of the second lumen.