Apparatus for guide-wire based advancement of a rotation assembly

• US 8,940,042 B2
• Filed: 06/07/2010
• Issued: 01/27/2015
• Est. Priority Date: 10/29/2009
• Status: Active Grant

• Current Assignee: Valtech Cardio Ltd (Edwards Lifesciences Corporation)
• Original Assignee: Valtech Cardio Ltd (Edwards Lifesciences Corporation)
• Inventors: Miller, Eran, Cabiri, Oz
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): SCHILLINGER, ANN M
• Application Number:
  US12/795,026
• Publication Number:
  US 20110106245A1
• Time in Patent Office: 1,695 Days
• Field of Search: 623 111- 154, 600/334, 600/358, 600/442
• US Class Current: 623/2.11
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/0441 the shaft being a rigid coil or spiral
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/0496 for tensioning sutures
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/2454 Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses

Abstract

Apparatus is provided for use with at least one tissue-adjustment device, including a tissue-engaging element having a distal portion configured to engage at least a first portion of tissue of a patient, and having a proximal portion. At least one docking station is coupled to the proximal portion of the tissue-engaging element and is configured to be coupled to the at least one tissue-adjustment device. The docking station includes a locking mechanism configured to lock the tissue-adjustment device to the tissue-engaging element. At least one guide member is reversibly coupled to the at least one docking station and is configured for facilitating slidable advancement of the at least one tissue-adjustment device toward the tissue-engaging element. Other applications are also described.

Claims

1. Apparatus for use with at least one tissue-adjustment device, the apparatus comprising:

a tissue-engaging element having a distal portion configured to engage at least a first portion of tissue of a patient, and having a proximal portion;

at least one docking station coupled to the proximal portion of the tissue-engaging element, the at least one docking station comprising a locking mechanism configured to lock the tissue-adjustment device to the docking station; and

at least one guide member reversibly coupled to the at least one docking station, the at least one guide member being configured for facilitating slidable advancement of the at least one tissue-adjustment device toward the docking station,

wherein the at least one docking station is configured to be coupled to the at least one tissue-adjustment device such that the at least one docking station is disposed between the at least one tissue-adjustment device and the tissue-engaging element.

2. The apparatus according to claim 1, wherein the guide member is looped around a portion of the docking station.

3. The apparatus according to claim 1, wherein the at least one docking station comprises two or more docking stations, and wherein the at least one guide member comprises two or more guide members, each guide member being reversibly coupled to a respective docking station.

4. The apparatus according to claim 1, further comprising the tissue-adjustment device, wherein the tissue-adjustment device has:

an upper surface and a lower surface,

at least one first opening at the upper surface,

at least one second opening at the lower surface, and

a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment device along the guide member.

5. The apparatus according to claim 4, wherein the tissue-adjustment device comprises a first coupling, and wherein the locking mechanism comprises a second coupling configured to be coupled to the first coupling.

6. The apparatus according to claim 5, wherein the second coupling comprises at least one depressed portion, and wherein the first coupling comprises at least one moveable baffle which is configured to engage the at least one depressed portion of the second coupling.

7. The apparatus according to claim 1, further comprising at least one flexible longitudinal member coupled at a first portion thereof to the tissue-adjustment device, wherein a second portion of the flexible longitudinal member is configured to be coupled to a second portion of tissue of the patient, and wherein the tissue-adjustment device is configured to adjust a length of the longitudinal member between the first and second portions of tissue.

8. The apparatus according to claim 7, wherein:

the first portion of tissue includes a first portion of cardiac tissue at a first intraventricular site,

the second portion of tissue includes at least one leaflet of an atrioventricular valve of the patient, and

the flexible longitudinal member comprises at least one artificial chordea tendinea.

9. The apparatus according to claim 7, wherein:

the tissue-adjustment device comprises a rotatable structure,

the at least one flexible longitudinal member is coupled at the first portion thereof to the rotatable structure, and

the rotatable structure is bidirectionally rotatable to adjust the degree of tension of the flexible longitudinal member.

10. The apparatus according to claim 9, wherein during rotation of the rotatable structure in a first rotational direction, successive portions of the flexible longitudinal member advance in a first advancement direction with respect to the rotatable structure and contact the rotatable structure, to pull the second portion of the flexible longitudinal member toward the tissue-adjustment device, and to draw the first and second portions of tissue toward each other.

11. The apparatus according to claim 9, further comprising a rotatable structure locking mechanism displaceable with respect to the rotatable structure, so as to:

release the rotatable structure during rotation of the rotatable structure, and

lock in place the rotatable structure following rotation of the rotatable structure.

12. The apparatus according to claim 9, wherein the rotatable structure comprises a spool, and wherein the at least one flexible longitudinal member is configured to be wound around the spool during the rotation of the spool in a first rotational direction.

13. The apparatus according to claim 12, wherein the first portion of the flexible longitudinal member is looped through a portion of the spool.

14. The apparatus according to claim 13, wherein the first portion of the flexible longitudinal member is wound around a portion of the spool, and wherein the first portion of the flexible longitudinal member is configured to be unwound from around the portion of the spool following coupling of the second portion of the flexible longitudinal member to the second portion of tissue of the patient.

15. The apparatus according to claim 1, further comprising the tissue-adjustment device, wherein the tissue-adjustment device comprises:

a rotatable structure; and

at least one flexible longitudinal member having a first portion thereof that is in contact with the rotatable structure, and a second portion thereof that is configured to be coupled to a second portion of tissue of the patient,

wherein during rotation of the rotatable structure in a first rotational direction, successive portions of the flexible longitudinal member advance in a first advancement direction with respect to the rotatable structure and contact the rotatable structure, and, pull the second portion of the flexible longitudinal member toward the tissue-adjustment device, and responsively, to draw the first and second portions of tissue toward each other.

16. The apparatus according to claim 15, wherein the guide member is looped around a portion of the docking station.

17. The apparatus according to claim 15, wherein the at least one docking station comprises two or more docking stations, and wherein the at least one guide member comprises two or more guide members, each guide member being reversibly coupled to a respective docking station.

18. The apparatus according to claim 15, wherein the tissue-adjustment device has:

an upper surface and a lower surface,

at least one first opening at the upper surface,

at least one second opening at the lower surface, and

a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment device along the guide member.

19. The apparatus according to claim 18, wherein the tissue-adjustment device comprises a first coupling, and wherein the docking station comprises a second coupling configured to be coupled to the first coupling.

20. The apparatus according to claim 19, wherein the second coupling comprises at least one depressed portion, and wherein the first coupling comprises at least one moveable baffle which is configured to engage the at least one depressed portion of the second coupling.

21. The apparatus according to claim 19, wherein the second coupling comprises a locking mechanism configured to lock the tissue-adjustment device to the tissue-engaging element.

22. The apparatus according to claim 15, wherein:

the first portion of tissue includes a first portion of cardiac tissue at a first intraventricular site,

the second portion of tissue includes at least one leaflet of an atrioventricular valve of the patient, and

the flexible longitudinal member comprises at least one artificial chordea tendinea.

23. The apparatus according to claim 15, wherein the rotatable structure is rotatable in a first rotational direction to apply tension to the flexible longitudinal member, and in a second rotational direction that is opposite the first rotational direction to slacken the flexible longitudinal member.

24. The apparatus according to claim 23, wherein during rotation of the rotatable structure in a first rotational direction thereof, successive portions of the flexible longitudinal member advance in a first advancement direction with respect to the rotatable structure and contact the rotatable structure, responsively, to pull the second portion of the flexible longitudinal member toward the tissue-adjustment device.

25. The apparatus according to claim 23, further comprising a rotatable structure locking mechanism, displaceable with respect to the rotatable structure so as to:

release the rotatable structure during rotation of the rotatable structure, and

lock in place the rotatable structure following rotation of the rotatable structure.

26. The apparatus according to claim 23, wherein the rotatable structure comprises a spool, and wherein the at least one flexible longitudinal member is configured to be wound around the spool during the rotation of the spool in the first rotational direction thereof.

27. The apparatus according to claim 26, wherein the first portion of the flexible longitudinal member is looped through a portion of the spool.

28. The apparatus according to claim 27, wherein the first portion of the flexible longitudinal member is wound around a portion of the spool, and wherein the first portion of the flexible longitudinal member is configured to be unwound from around the portion of the spool following the coupling of the second portion of the flexible longitudinal member to the second portion of tissue of the patient.

29. The apparatus according to claim 1, wherein the at least one docking station is fixedly coupled to the proximal portion of the tissue-engaging element.

30. The apparatus according to claim 1, wherein the locking mechanism is configured to lock the tissue-adjustment device to the docking station by the locking mechanism becoming locked to the tissue-adjustment device.