Blood flow measuring apparatus and brain activity measuring apparatus using the same

• US 8,945,018 B2
• Filed: 07/08/2009
• Issued: 02/03/2015
• Est. Priority Date: 02/14/2008
• Status: Active Grant

• Current Assignee: Cyberdyne Inc.
• Original Assignee: University of Tsukuba
• Inventors: Sankai, Yoshiyuki
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): TRAN, THO Q
• Application Number:
  US12/499,309
• Publication Number:
  US 20090270745A1
• Time in Patent Office: 2,036 Days
• Field of Search: 600504-507, 600/544, 600/545, 600/324
• US Class Current: 600/504
• CPC Class Codes: A61B 5/0042 for the brain
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/4064 Evaluating the brain A61B5/031, A61B5/369, A61B5/14553 take precedence
• CPC Class Codes: A61B 5/6814 Head

Abstract

A blood flow measuring apparatus includes a sensor unit including a light emitter configured to emit light onto a measurement area and a light receiver configured to receive the light transmitted through the measurement area; at least one more light receiver configured to receive the light transmitted through the measurement area; and a control part configured to measure a blood flow state of the measurement area according to signals outputted by the light receivers. The light emitted by the light emitter is received by the light receivers arranged at different distances from the light emitter and the light receivers output the signals responsive to the received light. The control part measures the blood flow state of the measurement area by performing an arithmetic process to cancel a component of oxygen saturation in the blood, said component being included in the signals outputted by the light receivers.

Claims

1. A blood flow measuring apparatus comprising:

a plurality of sensor units, each of the plurality of sensor units including a light emitting part configured to emit first light and second light onto a measurement area, a light receiving part configured to receive the first light and second light transmitted through the measurement area, and a brain wave measuring electrode configured to measure a brain wave and integrally formed on a peripheral surface of the light emitting part and the light receiving part, a wavelength of the first light being different from a wavelength of the second light, wherein the plurality of sensor units are provided at different positions from each other and have the identical configuration to each other;

at least one more light receiving part configured to receive the first light and second light transmitted through the measurement area, wherein said at least one more light receiving part functions as a light receiving part of a different sensor unit from the sensor unit including the at least one more light receiving part among the plurality of sensor units; and

a control part configured to measure a blood flow state of the measurement area according to signals outputted by the light receiving parts

wherein the first light and second light emitted by the light emitting part is received by the light receiving parts arranged at different distances from the light emitting part and the light receiving parts output the signals responsive to the received first light and second light, and wherein the control part is configured to make a light emitting part of one of the plurality of sensor units emit the first light and the second light, detect amounts of transmitted light of the first and second light received by light receiving parts of at least two of the plurality of sensor units that are separated at different distances from the one of the plurality of sensor units, and is configured to measure the brain activity state of the measurement area according to measurement data responsive to the amounts of the transmitted light of the first light and the second light, said measurement data being outputted by the light receiving parts of the at least two of the plurality of sensor units, and

the control part is configured to measure the blood flow state of the measurement area by performing an arithmetic process to cancel a component of oxygen saturation in the blood, and execute the arithmetic process to calculate a test subject'"'"'s red blood cell concentration as a function of only a hematocrit by ratioing between a red blood cell concentration in the first light and a red blood cell concentration in the second light,

wherein each of the plurality of sensor units includes an optical path separating member configured to have different refraction indexes with respect to light that proceeds from the light emitting part to the measurement area and light that proceeds from the measurement area to the light receiving part that is included it the sensor unit; and

the light emitting part emits the light and said light receiving part included in the sensor unit receives the light through the optical path separating member.

2. The blood flow measuring apparatus as claimed in claim 1, wherein the first light has a wavelength that is less influenced in an optical characteristic by the oxygen saturation in the blood than a wavelength of the second light.

3. The blood flow measuring apparatus as claimed in claim 2, wherein the control part compares first amounts of transmitted light of the first light received by the light receiving parts and second amounts of transmitted light of the second light received by the light receiving parts to measure the blood flow state of the measurement area.

4. The blood flow measuring apparatus as claimed in claim 3, wherein the control part measures the blood flow state of the measurement area according to measurement data responsive to the first and second amounts of the transmitted light, said measurement data being outputted by light receiving parts.

5. The blood flow measuring apparatus as claimed in claim 1, wherein the brain wave measuring electrode includes a contact terminal at the end thereof.

6. The blood flow measuring apparatus as claimed in claim 1, wherein the brain wave measuring electrode is formed of indium tin oxide.

7. A brain activity measuring apparatus comprising:

a blood flow measuring apparatus configured to measure a blood flow of a brain; and

a control part configured to measure an activity state of the brain according to a result of the measurement preformed by the blood flow measuring apparatus,

wherein the blood flow measuring apparatus comprises;

a plurality of sensor units, each of the plurality of sensor units including a light emitting part configured to emit first light and second light onto a measurement area and a light receiving part configured to receive the first light and second light transmitted through the measurement area, and a brain wave measuring electrode configured to measure a brain wave and integrally formed on a peripheral surface of the light emitting part and the light receiving part, a wavelength of the first light being different from a wavelength of the second light, wherein the plurality of sensor units are provided at different positions from each other and have the identical configuration to each other; and

at least one more light receiving part configured to receive the first light and second light transmitted through the measurement area,

wherein the light emitted by the light emitting part is received by the light receiving parts arranged at different distances from the light emitting part and the light receiving part output signals responsive to the received light, and

wherein said at least one more light receiving part functions as a light receiving part of a different sensor unit from the sensor unit including the at least one more light receiving part among the plurality of sensor units; and

the control part is configured to measure a blood flow state of the measurement area by performing an arithmetic process to cancel a component of oxygen saturation in the blood, and execute the arithmetic process to calculate a test subject'"'"'s red blood cell concentration as a function of only a hematocrit by ratioing between a red blood cell concentration in the first light and a red blood cell concentration in the second light,

wherein the control part is configured to make a light emitting part of one of the plurality of sensor units emit the first light and the second light, detect amounts of transmitted light of the first and second light received by light receiving parts of at least two of the plurality of sensor units that are separated at different distances from the one of the plurality of sensor units, and measure the brain activity state of the measurement area according to measurement data responsive to the amounts of the transmitted light of the first light and the second light, said measurement data being outputted by the light receiving parts of the at least two of the plurality of sensor units,

wherein each of the plurality of sensor units includes an optical path separating member configured to have different refraction indexes with respect to light that proceeds from the light emitting part to the measurement area and light that proceeds from the measurement area to the light receiving part that is included in the sensor unit; and

the light emitting part emits the light and said light receiving part included in the sensor unit receives the light through the optical path separating member.

8. The brain activity measuring apparatus as claimed in claim 7, wherein the first light has a wavelength that is less influenced in an optical characteristic by the oxygen saturation in the blood than a wavelength of the second light.

9. The brain activity measuring apparatus as claimed in claim 7, wherein the control part sequentially makes the light emitting parts of all the sensor units emit the first light and the second light, detects an intensity of the light received by light receiving parts of at least two sensor units which are separated at different distances from the sensor unit which emits light, and measures the brain activity state of the measurement area according to measurement data responsive to the amounts of transmitted light of the first light and the second light, said measurement data being outputted by the said light receiving parts of the at least two sensor units.

10. The brain activity measuring apparatus as claimed in claim 7, wherein the brain wave measuring electrode includes a contact terminal at the end thereof.

11. The brain activity measuring apparatus as claimed in claim 7, wherein the brain wave measuring electrode is formed of indium tin oxide.