System and method for attaching soft tissue to an implant
First Claim
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1. A composite bioprosthetic comprisinga metal implant that comprises a porous region, wherein the porous region exhibits a nano-textured surface;
- a calcified material layer coating the nano-textured surface; and
a scaffold layer comprising a biocompatible polymer matrix and growth factors, wherein at least a portion of the scaffold layer is in contact with the calcified material layer.
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Abstract
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein the porous region exhibits a nano-textured surface, and a biocompatible polymer matrix coating the nano-textured surface. The polymer matrix coating comprises a naturally occurring extracellular matrix with biocompatible inorganic materials distributed within the matrix, or a biocompatible polymer and an osteo-inductive agent.
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Citations
9 Claims
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1. A composite bioprosthetic comprising
a metal implant that comprises a porous region, wherein the porous region exhibits a nano-textured surface; -
a calcified material layer coating the nano-textured surface; and a scaffold layer comprising a biocompatible polymer matrix and growth factors, wherein at least a portion of the scaffold layer is in contact with the calcified material layer. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A composite bioprosthetic comprising
a metal implant that comprises a porous region, wherein the porous region exhibits a nano-textured surface; -
a calcified material layer coating the nano-textured surface; and a scaffold layer comprising a biocompatible polymer matrix and growth factors, wherein at least a portion of the scaffold layer is in contact with the calcified material layer; and an extender layer coupled to the scaffold layer, the extender layer comprising a submucosal matrix, and a synthetic mesh member coupled to the submucosal matrix. - View Dependent Claims (8, 9)
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Specification