Method for using a pulse oximetry signal to monitor blood pressure

• US 8,951,204 B2
• Filed: 05/04/2012
• Issued: 02/10/2015
• Est. Priority Date: 05/04/2012
• Status: Active Grant

• Current Assignee: Guy P. Curtis And Frances L. Curtis Trust
• Original Assignee: Guy P. Curtis And Frances L. Curtis Trust
• Inventors: Curtis, Guy P.
• Primary Examiner(s): BERHANU, ETSUB D
• Application Number:
  US13/464,732
• Publication Number:
  US 20130296671A1
• Time in Patent Office: 1,012 Days
• Field of Search: 600/324, 600/485
• US Class Current: 600/485
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/02116 of pulse wave amplitude A61B5/02225 takes precedence
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

A system for continuously monitoring the blood pressure of a patient over an extended time interval requires using a blood pressure measuring unit (e.g. a sphygmomanometer) to calibrate an oximeter. Specifically, the oximeter is used to continuously detect and measure amplitudes for each blood flow pulse of the patient. Periodically, the sphygmomanometer is used to measure blood pressures (systolic and diastolic) in an artery of the patient. Immediately after the measurement cycle is completed, a computer correlates the measured systolic pressure with the pulse amplitude that is detected by the oximeter. Thereafter, the pulse amplitudes that are detected by the oximeter are used as indications of variations in the systolic pressure during the extended time interval that follows.

Claims

1. A system for continuously monitoring the blood pressure of a patient for an extended period of time which comprises:

a unit for measuring blood pressures in an artery of the patient during a measurement cycle, wherein the measurement cycle has a beginning and an end, and wherein a systolic pressure (p_systolic) is measured at a time “

t₀”

at the beginning of the measurement cycle and a diastolic pressure (p_diastolic) is measured at the end of the measurement cycle;

a device for detecting blood pressure pulses in the cardio-vasculature of a patient during the measurement cycle, wherein a first pulse near the beginning of the measurement cycle has an amplitude value “

V₁”

, and a second pulse with an amplitude value “

V₂”

is detected at the end of the measurement cycle wherein V₁ is detected by the detecting device and a first pressure p₁ is measured by the measuring unit at a determined time (“

t₁”

) in the measurement cycle, and wherein an initial pressure drop Δ

₁ is established at the time t₁, with Δ

₁ being a correction factor equal to the difference between p_systolic and p₁ (Δ

₁=p_systolic−

p₁); and

a computer for correlating the systolic pressure (p_systolic) with “

V₂+Δ

₁”

, to establish a correlation therebetween, and for thereafter using the correlation to identify variations in pulse amplitudes V₂ detected by the detecting device as indications of corresponding variations in systolic pressures (p_systolic) during the extended period of time following the measurement cycle.

2. A system as recited in claim 1 wherein the computer compares a pulse differential “

Δ

_v”

(Δ

_v=V₁−

V₂) directly with a pressure differential “

Δ

_p”

(Δ

_p=p₁−

p_diastolic) to correlate pulse metrics of Δ

_v with pressure metrics of Δ

_p.

3. A system as recited in claim 2 wherein p_systolic is equated with V₂+Δ

₁ and p_diastolic is equated with V₁.

4. A system as recited in claim 3 further comprising a monitor for presenting the indications of systolic pressure during the extended period of time.

5. A system as recited in claim 3 wherein the detecting device is an oximeter and the measuring unit is a sphygmomanometer.

6. A system as recited in claim 3 wherein the extended period of time is greater than fifteen minutes.

7. A system as recited in claim 3 wherein the pulse amplitude values V₁ and V₂ are detected continuously during the extended period of time.

8. A method for continuously monitoring the blood pressure of a patient for an extended period of time which comprises the steps of:

measuring blood pressures in an artery of the patient with a unit during a measurement cycle, wherein a systolic pressure (p_systolic) is measured at a time “

t₀”

at the beginning of the measurement cycle and a diastolic pressure (p_diastolic) is measured at a time “

t₂”

at the end of the measurement cycle;

detecting blood pressure pulses in the cardio-vasculature of the patient with a device, wherein each pulse has a pulse amplitude;

detecting a pulse amplitude value “

V₁”

at a determined time “

t₁”

;

establishing an initial pressure drop “

Δ

₁”

, from p_systolic to p₁, at the determined time “

t₁”

using a computer;

detecting a pulse amplitude value “

V₂”

at the time “

t₂”

; and

using the computer to compare a pulse differential “

Δ

_v”

(Δ

_v=V₁−

V₂) directly with a pressure differential “

Δ

_p”

(Δ

_p=p₁−

p_diastolic) to correlate pulse metrics of Δ

_v with pressure metrics of Δ

_p and to equate p_systolic with V₂+Δ

₁ and p_diastolic with V₁ during the extended period of time.

9. A method as recited in claim 8 further comprising the steps of:

monitoring blood pressure pulses in the detecting step during the extended period of time; and

presenting a visual display of variations in the systolic pressures during the extended period of time.

10. A method as recited in claim 8 wherein the extended period of time immediately follows the measurement cycle.

11. A method as recited in claim 8 wherein the extended period of time is greater than fifteen minutes.

12. A method as recited in claim 8 wherein pulse amplitudes are continuously detected in the detecting step during the extended period of time.

13. A method as recited in claim 8 wherein the detecting step is accomplished using an oximeter, and the measuring step is accomplished using a sphygmomanometer.

14. A tangible computer program product for continuously monitoring the blood pressure of a patient for an extended period of time, wherein the computer program product comprises program sections that, when executed, cause a computer to perform the following method steps:

measuring a systolic pressure (p_systolic) at a time “

t₀”

at the beginning of a measurement cycle;

detecting a pulse amplitude value “

V₁” and

a pressure “

p₁”

at a determined time “

t₁”

;

establishing an initial pressure drop “

Δ

₁”

, from p_systolic to p₁, at the determined time “

t₁”

;

detecting a pulse amplitude value “

V₂”

at a time “

t₂”

at the end of the measurement cycle;

comparing a pulse differential “

Δ

_v”

(Δ

_v=V₁−

V₂) directly with a pressure differential “

Δ

_p”

(Δ

_p=p_diastolic) to correlate pulse metrics of Δ

_v with pressure metrics of Δ

_p; and

equating p_systolic with V₂+Δ

₁ and p_diastolic with V₁ during an extended period of time.

15. A computer program product as recited in claim 14 wherein the extended period of time immediately follows the measurement cycle, wherein the extended period of time is greater than fifteen minutes, and wherein pulse amplitudes are continuously detected during the extended period of time.