Subchondral treatment of joint pain

• US 8,951,261 B2
• Filed: 11/19/2010
• Issued: 02/10/2015
• Est. Priority Date: 11/20/2009
• Status: Active Grant

• Current Assignee: Zimmer Knee Creations, Inc. (Zimmer Biomet Holdings, Inc.)
• Original Assignee: Zimmer Knee Creations, Inc. (Zimmer Biomet Holdings, Inc.)
• Inventors: Sharkey, Peter F., Leinberry, Charles F., Cohen, Steven B., Bagga, Charanpreet S., Erbe, Erik M.
• Primary Examiner(s): SEVILLA, CHRISTIAN ANTHONY
• Application Number:
  US12/950,355
• Publication Number:
  US 20110125157A1
• Time in Patent Office: 1,544 Days
• Field of Search: 604/218, 606/80, 606/86.R, 606/88, 606/92, 606/93, 606/94
• US Class Current: 606/92
• CPC Class Codes: A61B 17/1637 Hollow drills or saws producing a curved cut, e.g. cylindrical A61B10/025, A61B17/1695 take precedence
• CPC Class Codes: A61B 17/1697 specially adapted for wire insertion
• CPC Class Codes: A61B 17/17 Guides or aligning means for drills , mills, pins or wires
• CPC Class Codes: A61B 17/1742 for the hip
• CPC Class Codes: A61B 17/1764 for the knee
• CPC Class Codes: A61B 17/1775 for the foot or ankle
• CPC Class Codes: A61B 17/1778 for the shoulder
• CPC Class Codes: A61B 17/68 Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin bone staples A61B17/0642
• CPC Class Codes: A61B 17/8802 Equipment for handling bone cement or other fluid fillers
• CPC Class Codes: A61B 17/8805 for introducing fluid filler into bone or extracting it A61B17/7097, A61B17/8833 take precedence
• CPC Class Codes: A61B 17/8872 Instruments for putting said fixation devices against or away from the bone A61B17/7074, A61B17/808 take precedence
• CPC Class Codes: A61B 17/8897 Guide wires or guide pins
• CPC Class Codes: A61B 17/90 Guides therefor
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

The embodiments provide devices and methods that both strengthen the bone and stimulate the bone. Bone fractures or non-unions are stabilized, integrated or healed, which results in reduction of a bone defect, such as a bone marrow lesion or edema. In addition, the distribution of forces in a joint are restored or altered to relieve pain. In general, a joint is evaluated by taking an image of the joint and one or more subchondral defects are detected. At least one of the subchondral defects may be diagnosed as the source of pain and an extent of treatment for the subchondral defect is determined. The disclosed devices and techniques are particularly suited for treating chronic defects or injuries, where the patient'"'"'s natural healing response has not resolved the defect. The present disclosure also provides several exemplary treatment modalities for the different extents of treatment needed.

Claims

1. A system for treating joint pain comprising:

an injectable material for biological stimulation of a healing response to a subchondral defect in a subchondral region of a bone adjacent to the joint;

an injector tool for delivery of the material; and

an instrument for guiding the tool to a target location in the bone, the instrument comprising;

a first portion having a first guide section configured to guide the tool to the target location;

a reference probe extending from the first portion having a tip configured for placement on the bone, without breaching an outer surface of the bone, and proximate a selected anatomical landmark; and

a handle portion coupled to the first portion and having a second guide section configured to guide a tool to the target location;

wherein the first guide section comprises portals configured to guide the tool towards the tip of the reference probe, and the second guide section comprises portals configured to guide the tool at an acute angle with respect to the reference probe.

2. The system of claim 1, wherein the reference probe is configured to rest against the anatomical landmark on the bone.

3. The system of claim 1, wherein the portals of the first and second guide sections are configured to guide the tool into the subchondral region of the bone.

4. The system of claim 1, wherein the instrument is a unitary body.

5. The system of claim 1, wherein the handle portion is detachable from the first portion.

6. The system of claim 1, wherein the handle portion is configured with a radius of curvature that provides a plurality of acute angles of approach to the target location.

7. The system of claim 1, further including a drilling tool for drilling into the subchondral region of the bone.

8. The system of claim 1, wherein the injectable material is a bone cement, a bone void filler, or a bone substitute material.

9. The system of claim 8, wherein the injectable material further includes a bone growth stimulating factor.

10. The system of claim 1, wherein the portals of the first guide section define trajectories that are substantially parallel to the reference probe.

11. The system of claim 1, wherein the portals of the second guide section comprise a set of differently angled portals.