Transcranial magnetic stimulation field shaping
First Claim
1. A Transcranial Magnetic Stimulation (TMS) system for stimulating a subject'"'"'s neuronal tissue configured for shaping an emitted magnetic field to modulate a brain target, the system including:
- a primary TMS electromagnet configured to apply TMS to the subject; and
one or more secondary TMS electromagnets, configured to be activated concurrently with the primary TMS electromagnet to apply TMS to the subject and to shape a magnetic field emitted by the primary TMS electromagnet, wherein the one or more secondary TMS electromagnets are configured to emit a magnetic field that is concurrent with and shapes the magnetic field emitted by the primary TMS electromagnet; and
one or more power sources comprising an oscillator for delivering a pulsed power to the primary TMS electromagnet and one or more secondary TMS electromagnets.
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Accused Products
Abstract
Described herein are Transcranial Magnetic Simulation (TMS) systems and methods of using them for emitting focused, or shaped, magnetic fields for TMS. In particular, described herein are arrays of TMS electromagnets comprising at least one primary (e.g., central) TMS electromagnet and a plurality of secondary (e.g., lateral or surrounding) TMS electromagnets. The secondary TMS electromagnets are arranged around the primary TMS electromagnet(s), and are typically configured to be synchronously fired with the primary TMS electromagnets. Secondary TMS electromagnets may be fired at a fraction of the power used to energize the primary TMS electromagnet to shape the resulting magnetic field. The secondary TMS electromagnets may be stimulated at opposite polarity to the primary TMS electromagnet(s). Focusing in this manner may prevent or reduce stimulation of adjacent non-target brain regions.
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Citations
21 Claims
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1. A Transcranial Magnetic Stimulation (TMS) system for stimulating a subject'"'"'s neuronal tissue configured for shaping an emitted magnetic field to modulate a brain target, the system including:
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a primary TMS electromagnet configured to apply TMS to the subject; and one or more secondary TMS electromagnets, configured to be activated concurrently with the primary TMS electromagnet to apply TMS to the subject and to shape a magnetic field emitted by the primary TMS electromagnet, wherein the one or more secondary TMS electromagnets are configured to emit a magnetic field that is concurrent with and shapes the magnetic field emitted by the primary TMS electromagnet; and one or more power sources comprising an oscillator for delivering a pulsed power to the primary TMS electromagnet and one or more secondary TMS electromagnets. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A Transcranial Magnetic Stimulation (TMS) system for stimulating a subject'"'"'s neuronal tissue, the system including:
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a primary TMS electromagnet configured to apply Transcranial Magnetic Stimulation to the subject; and at least one secondary TMS electromagnet configured to shape a magnetic field emitted by the primary TMS electromagnet, and wherein the at least one secondary TMS electromagnet is configured to be activated when the primary TMS electromagnet is activated and to emit a magnetic field that is of opposite polarity and is concurrent with and shapes the magnetic field emitted by the primary TMS electromagnet; and one or more power sources comprising an oscillator for delivering a pulsed power to the primary TMS electromagnet and the secondary TMS electromagnet.
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13. A Transcranial Magnetic Stimulation (TMS) system for stimulating a subject'"'"'s neuronal tissue, the system including:
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a primary TMS electromagnet configured to apply Transcranial Magnetic Stimulation to the subject; a plurality of secondary TMS electromagnets configured to shape a magnetic field emitted by the primary TMS electromagnet, wherein the secondary TMS electromagnets are configured to be activated concurrently with activation of the primary TMS electromagnet and to emit a magnetic field that is opposite in polarity and concurrent with the magnetic field emitted by the primary TMS electromagnet; and one or more power sources comprising an oscillator for delivering a pulsed power to the primary TMS electromagnet and the secondary TMS electromagnets, and wherein the primary TMS electromagnet is configured to be positioned between the secondary TMS electromagnets around the patient'"'"'s head. - View Dependent Claims (14, 15, 16, 17, 18)
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19. A method of performing Transcranial Magnetic Stimulation (TMS) of target deep brain structures by shaping a magnetic field emitted by a primary TMS electromagnet, the method comprising:
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positioning a primary TMS electromagnet between a plurality of secondary TMS electromagnets around a subject'"'"'s head; and shaping the magnetic field emitted by the primary TMS electromagnet to modulate a deep brain target by simultaneously emitting a magnetic field from the primary TMS electromagnet and each of the plurality of secondary TMS electromagnets, modulating the deep brain target; and one or more power sources comprising an oscillator for delivering a pulsed power to the primary TMS electromagnet and the secondary TMS electromagnets. - View Dependent Claims (20, 21)
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Specification