Compositions and methods for treating skin with extract from

• US 8,956,624 B2
• Filed: 11/21/2008
• Issued: 02/17/2015
• Est. Priority Date: 12/19/2007
• Status: Active Grant

• Current Assignee: ELC Management LLC (The Estee Lauder Companies Inc.)
• Original Assignee: ELC Management LLC (The Estee Lauder Companies Inc.)
• Inventors: Schnittger, Steven F., Maes, Daniel H., Sullivan, Michael
• Primary Examiner(s): HOFFMAN, SUSAN COE
• Application Number:
  US12/306,372
• Publication Number:
  US 20100203077A1
• Time in Patent Office: 2,279 Days
• Field of Search: None
• US Class Current: 424/195.15
• CPC Class Codes: A61K 8/9711 Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
• CPC Class Codes: A61K 8/9728 Fungi, e.g. yeasts
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin

Abstract

Compositions for treating skin containing at least one extract from the genus Trametes and at least one viscosity enhancing synthetic polymer, and methods for whitening skin, treating skin for improvement, or treating skin disorders associated with pigmentation such as uneven pigmentation, skin mottling, or age spots or other dermatological disorders such as eczema, rosacea, hyperkeratinization, and so on.

Claims

1. A method for lightening the color of uneven skin pigmentation, skin mottling, or age spots due to exposure to UV radiation comprising applying to the areas of skin exposed to UV radiation, at least once per day a topical composition comprising (a) at least one extract from Trametes versicolor in an amount sufficient to inhibit tyrosinase, and (b) at least one viscosity enhancing synthetic polymer for a period of time sufficient to cause the uneven skin pigmentation, skin mottling, or age spots to become lighter in color.

2. The method of claim 1 wherein the skin mottling, or age spots are due to exposure to UVB radiation.

3. The method of claim 2 wherein the skin has been exposed to UVB radiation and the composition is applied to the uneven skin pigmentation, skin mottling or age spots in the form of a skin cream or lotion.

4. The method of claim 2 wherein the viscosity enhancing synthetic polymer is carbomer or acrylates C10-30 alkyl acrylates crosspolymer.

5. The method of claim 4 wherein the Trametes versicolor extract is also a skin moisturizer.

6. The method of claim 2 wherein the extract is from Trametes versicolor and the composition additionally comprises whey protein.

7. The method of claim 6 wherein the Trametes versicolor extract is a tyrosinase inhibitor and a skin moisturizer.

8. The method of claim 6 wherein the Trametes versicolor extract is obtained by extraction with water, alkanols, or volatile organic solvents.

9. The method of claim 6 wherein the Trametes versicolor extract is present from 0.00001-40% by weight of the total composition.

10. The method of claim 6 wherein the composition is applied in the form of a skin cream or lotion.

11. The method of claim 10 wherein the composition additionally comprises one or more humectants.

12. The method of claim 1 wherein the skin has been exposed to UVB radiation and the composition is applied one or more times a day for at least 18 days in the form of a skin cream or lotion, toner, facial cleanser, serum, or color cosmetic composition and the treated areas become lighter in color by at least 15 days after first treatment.

13. The method of claim 12 wherein the skin has been exposed to both UVA and UVB radiation.

14. The method of claim 1 wherein the extract is Trametes versicolor obtained by extraction of the Trametes plant material with water, alkanols, or volatile organic solvents.

15. The method of claim 14 wherein the extract is present at 0.00001-40% by weight of the total composition.

16. The method of claim 15 wherein the composition additionally comprises one or more botanical extracts.

17. The method of claim 16 wherein the composition additionally contains one or more botanical extracts derived from herbs, roots, flowers, fruit, or seeds.

18. The method of claim 1 wherein the composition consists essentially of:

a tyrosinase-inhibiting effective amount of Trametes versicolor; and

a viscosity enhancing synthetic polymer selected from carbomer Acrylates C10-30 alkylacrylates crosspolymer and mixtures thereof.