Sample analyzer and computer program product

• US 8,968,661 B2
• Filed: 05/10/2013
• Issued: 03/03/2015
• Est. Priority Date: 02/01/2007
• Status: Active Grant

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Nagai, Takaaki, Narisada, Noriyuki, Fukuma, Daigo
• Primary Examiner(s): Sines, Brian J
• Application Number:
  US13/891,667
• Publication Number:
  US 20130252276A1
• Time in Patent Office: 662 Days
• Field of Search: 422/50, 422/68.1, 422/81, 422/82, 422/63, 422/64, 422/65, 422/66, 422/67, 436/43, 436/164, 436/63
• US Class Current: 422/81
• CPC Class Codes: G01N 15/12 by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
• CPC Class Codes: G01N 15/1459 the analysis being performed on a sample stream
• CPC Class Codes: G01N 2015/012 Red blood cells
• CPC Class Codes: G01N 2015/014 Reticulocytes
• CPC Class Codes: G01N 2015/016 White blood cells
• CPC Class Codes: G01N 2015/1486 Counting the particles
• CPC Class Codes: G01N 33/5091 for testing the pathological state of an organism
• CPC Class Codes: G01N 33/5094 for blood cell populations red blood cells G01N33/80
• CPC Class Codes: G01N 33/721 Haemoglobin
• CPC Class Codes: G01N 33/726 Devices
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/113332 with conveyance of sample along a test line in a container or rack

Abstract

A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.

Claims

1. A sample analyzer comprising:

a controller configured to receive a designation of one measurement mode among a plurality of measurement modes including at least a blood measurement mode for measuring the blood sample and a body fluid measurement mode for measuring the body fluid sample,

a measuring part for preparing a measurement sample from a blood sample or a body fluid sample that differs from the blood sample, measuring the prepared measurement sample, and obtaining characteristic information representing characteristics of components in the measurement sample; and

wherein

the controller controls the measuring part to prepare a blank sample, which is free from a component derived from the blood sample or body fluid sample, and to measure the blank sample when the measurement mode is switched from the blood measurement mode to the body fluid measurement mode, and

the controller analyzes the characteristic information to determine an amount of the components in the measurement sample.

2. The sample analyzer according to claim 1, wherein

the controller is configured to analyze the characteristic information to quantify an amount of component in the blank sample.

3. The sample analyzer according to claim 2, wherein

the controller disallows to receive an instruction to start a measurement of a body fluid sample when the amount of component in the blank sample is equal to or excess over a first threshold value.

4. The sample analyzer according to claim 3, wherein

the controller controls the measuring part to prepare and measure the blank sample again when the amount of component in the blank sample is equal to or excess over the first threshold value.

5. The sample analyzer according to claim 3 or 4, wherein

the controller allows to receive the instruction to start a measurement of a body fluid sample when the amount of component in the blank sample is less than the first threshold value.

6. The sample analyzer according to claim 5, wherein

the controller controls the measuring part to start the measurement of a body fluid sample when the instruction is received, and

the controller sets the measuring part in a standby state where the measuring part is ready to measure a next body fluid sample when the amount of component in the body fluid sample is less than a second threshold value.

7. The sample analyzer according to claim 4 further comprising a display, and wherein

the controller controls the display to display a screen including a key to receive an instruction to start a washing of the measuring part when a predetermined number of times of the measurement of blank sample have been completed but the amount of component in the blank sample is still equal to or excess over the first threshold value.

8. The sample analyzer according to claim 7, wherein

the controller controls the measuring part to perform the washing by use of a washing solution when the key is operated.

9. The sample analyzer according to claim 1, wherein

the controller controls the measuring part to prepare and measure the blank sample when the sample analyzer is tuned ON, and sets the blood measurement mode as a default measurement mode.

10. The sample analyzer according to claim 1, wherein

the controller is configured to compare a measurement result of the blank sample with predetermined criteria for evaluating a background of the measurement, and

the criteria includes:

a first criterion which is applied to a measurement of a blank sample carried out in the blood measurement mode; and

a second criterion which is applied to a measurement of a blank sample carried out in the body fluid measurement mode, the second criterion being more strict than the first criterion.