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Attachment of a biomaterial to tissue

  • US 8,968,760 B2
  • Filed: 02/24/2012
  • Issued: 03/03/2015
  • Est. Priority Date: 04/27/2011
  • Status: Active Grant
First Claim
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1. A method for attaching an implant to a tissue comprising:

  • applying a sprayable material to a tissue, the sprayable material comprising at least one functional group capable of attaching said sprayable material to the tissue and further comprising at least one first nucleotide;

    allowing the at least one functional group on the sprayable material to attach to the tissue;

    applying to the sprayable material an implant having a surface possessing at least one second nucleotide complementary to the at least one first nucleotide on the sprayable material, wherein the sprayable material comprises a multi-arm polyethylene glycol and the sprayable material is not the implant; and

    permitting the at least one first nucleotide on the sprayable material to bond with the second nucleotide on the surface of the implant so as to allow the implant to bind to the sprayable material, thereby attaching the implant to the target tissue.

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