Attachment of a biomaterial to tissue
First Claim
1. A method for attaching an implant to a tissue comprising:
- applying a sprayable material to a tissue, the sprayable material comprising at least one functional group capable of attaching said sprayable material to the tissue and further comprising at least one first nucleotide;
allowing the at least one functional group on the sprayable material to attach to the tissue;
applying to the sprayable material an implant having a surface possessing at least one second nucleotide complementary to the at least one first nucleotide on the sprayable material, wherein the sprayable material comprises a multi-arm polyethylene glycol and the sprayable material is not the implant; and
permitting the at least one first nucleotide on the sprayable material to bond with the second nucleotide on the surface of the implant so as to allow the implant to bind to the sprayable material, thereby attaching the implant to the target tissue.
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Accused Products
Abstract
A method for attaching an implant to tissue is disclosed. In embodiments, a method includes applying a sprayable material to tissue, the sprayable material possessing functional groups capable of binding to tissue. The sprayable material also possesses functional groups capable of binding to an implant. In embodiments, the functional groups capable of binding to an implant include nucleotides. In such a case, the implant possesses complementary nucleotides capable of binding to the nucleotides on the sprayable material, thereby permitting hydrogen binding between the two. The implant may thus be affixed to tissue, and repositioned as necessary, prior to more permanent attachment utilizing means such as sutures, tacks, etc.
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Citations
18 Claims
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1. A method for attaching an implant to a tissue comprising:
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applying a sprayable material to a tissue, the sprayable material comprising at least one functional group capable of attaching said sprayable material to the tissue and further comprising at least one first nucleotide; allowing the at least one functional group on the sprayable material to attach to the tissue; applying to the sprayable material an implant having a surface possessing at least one second nucleotide complementary to the at least one first nucleotide on the sprayable material, wherein the sprayable material comprises a multi-arm polyethylene glycol and the sprayable material is not the implant; and permitting the at least one first nucleotide on the sprayable material to bond with the second nucleotide on the surface of the implant so as to allow the implant to bind to the sprayable material, thereby attaching the implant to the target tissue. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification