Analyte sensors and methods
First Claim
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1. A method for determining the concentration of an analyte in a sample, the method comprising:
- receiving a sample to an analyte sensor, wherein the analyte sensor comprises a working electrode and a counter electrode;
electrolysing the sample;
measuring current as a function of time;
predicting a first total signal value for complete electrolysis of the analyte from the measured current decay prior to a first time during electrolysis and an extrapolated current decay subsequent the first time during electrolysis;
determining a data collection endpoint, wherein the data collection endpoint is a predetermined percentage of the predicted first signal value;
measuring current until the data collection endpoint;
calculating a second total signal value from the measured current decay prior to the data collection endpoint and an extrapolated current decay subsequent the data collection point; and
determining the concentration of the analyte based on the calculated second signal value.
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Abstract
Methods of determining analyte concentration. The methods use a fraction of the predicted total charge, from analyte electrolysis, instead of using time, for determination of a data collection endpoint. The total charge is then extrapolated from the data collection endpoint. The analyte concentration is determined from the total charge.
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9 Claims
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1. A method for determining the concentration of an analyte in a sample, the method comprising:
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receiving a sample to an analyte sensor, wherein the analyte sensor comprises a working electrode and a counter electrode; electrolysing the sample; measuring current as a function of time; predicting a first total signal value for complete electrolysis of the analyte from the measured current decay prior to a first time during electrolysis and an extrapolated current decay subsequent the first time during electrolysis; determining a data collection endpoint, wherein the data collection endpoint is a predetermined percentage of the predicted first signal value; measuring current until the data collection endpoint; calculating a second total signal value from the measured current decay prior to the data collection endpoint and an extrapolated current decay subsequent the data collection point; and determining the concentration of the analyte based on the calculated second signal value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification