Removable lung reduction devices, systems, and methods

• US 8,974,484 B2
• Filed: 03/06/2013
• Issued: 03/10/2015
• Est. Priority Date: 09/11/2001
• Status: Expired due to Fees

• Current Assignee: Gyrus ACMI, Inc. (Olympus Corporation)
• Original Assignee: Spiration, Inc. (Olympus Corporation)
• Inventors: Alferness, Clifton A., Gonzalez, Hugo X., Dillard, David H.
• Primary Examiner(s): Philogene, Pedro
• Application Number:
  US13/787,052
• Publication Number:
  US 20130345737A1
• Time in Patent Office: 734 Days
• Field of Search: 606/108, 606/198, 606/191, 606/106, 606/200, 623/23.65, 12820714-20716, 128/200.26
• US Class Current: 606/198
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61F 2002/043 Bronchi
• CPC Class Codes: A61M 16/0404 with means for selective or partial lung respiration

Abstract

An air passageway obstruction device includes a frame structure and a flexible membrane overlying the frame structure. The frame structure is collapsible upon advancement of the device into the air passageway, expandable into a rigid structure upon deploying in the air passageway and recollapsible upon removal from the air passageway. The flexible membrane obstructs inhaled air flow into a lung portion communicating with the air passageway. The device may be removed after deployment in an air passageway by recollapsing the device and pulling the device proximally through a catheter.

Claims

1. A device for insertion into a lung airway passage, the device having a proximal end and a distal end and comprising:

a plurality of elongate frame supports configured to transition between a collapsed configuration and an expanded configuration, one or more of the frame supports having;

an anchor portion comprising a piercing portion configured to pierce an airway wall and a bent portion configured to limit a depth to which the piercing portion pierces an airway wall, the piercing portion extending from a bifurcated portion of the anchor portion; and

a membrane support portion connected to the anchor portion, the membrane support portion having a convex side and a concave side;

a flexible membrane forming a one-way valve and having an axial centerline and overlaying at least a portion of the convex side of the membrane support portion; and

a ring member, the anchor portion connected to the ring member and extending from the ring member in a distal direction away from the axial centerline when the elongate frame supports are in the expanded configuration.

2. The device of claim 1, wherein the flexible membrane has an open proximal end and a closed distal end.

3. The device of claim 1, wherein the flexible membrane permits passage of airflow in a proximal direction and obstructs airflow in a distal direction.

4. The device of claim 1, wherein a length of the anchor portion parallel to the axial centerline increases when the elongate frame supports transition from the expanded configuration to the collapsed configuration.

5. The device of claim 1, wherein a radial length of the anchor portion perpendicular to the axial centerline decreases when the elongate frame supports transition from the expanded configuration to the collapsed configuration.

6. The device of claim 1, wherein the device fits within a working portion of a catheter when the elongate frame supports are in the collapsed configuration.

7. The device of claim 1, wherein a proximal end of each membrane support portion curves toward the axial centerline.

8. A medical device for treating lung conditions, the medical device comprising:

an occlusion portion having an open proximal end and a closed distal end, the occlusion portion comprising;

a plurality of frame members having a convex side and a concave side; and

a flexible membrane forming a one-way valve and overlaying at least a portion of the convex side of the frame members; and

an anchor portion connected to the occlusion portion and comprising;

an ring member; and

a plurality of anchors extending from the ring member in a distal direction, one or more of the anchors comprising a piercing tip extending from a bifurcated portion of the anchor portion and a bent portion, the bent portion limiting a depth to which the piercing tip pierces an airway wall when the medical device is deployed in an airway passage.

9. The medical device of claim 8, wherein the occlusion portion is configured to transition between an occluding configuration and a collapsed configuration.

10. The medical device of claim 8, wherein the anchors engage with walls of an airway passage to inhibit movement of the medical device in the airway passage when the device is deployed in the airway passage.

11. The medical device of claim 8, wherein each of the piercing tips extends from a bifurcated portion of the one or more the anchors.

12. The medical device of claim 8, wherein the occlusion portion has an axial centerline.

13. The medical device of claim 8, wherein the medical device fits within a catheter when in a collapsed configuration.

14. The medical device of claim 8, wherein the flexible membrane is positioned at least partially on an outer surface of the frame members.

15. The medical device of claim 8, wherein the open proximal end of the occlusion portion engages with airway wall when the medical device is deployed in an airway passage.

16. The medical device of claim 8, wherein the occlusion portion partially collapses to permit airflow in a proximal direction when the medical device is deployed in an airway passage.

17. The medical device of claim 8, wherein a proximal end of each of the frame members bends toward an axial centerline of the occlusion portion.