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Method for determining presence of carcinomic cells with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine

  • US 8,975,038 B2
  • Filed: 07/16/2013
  • Issued: 03/10/2015
  • Est. Priority Date: 11/17/2000
  • Status: Expired due to Fees
First Claim
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1. A method to determine if a sample of cells contains dysplastic or carcinomic cells, the method comprising the steps of:

  • contacting the sample with a solution of 5,10,15,20-tetrakis(carboxyphenyl) porphine (TCPP) under conditions permitting binding of the TCPP to components of the dysplastic or carcinomic cells, if any are present, wherein the solution of TCPP comprises the TCPP pre-dissolved in basified alcohol; and

    detecting TCPP fluorescence in the sample, the presence of TCPP fluorescence being indicative that the sample contains dysplastic or carcinomic cells.

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