Apparatus and method for irradiating a scattering medium

• US 8,976,433 B2
• Filed: 12/16/2011
• Issued: 03/10/2015
• Est. Priority Date: 12/17/2010
• Status: Active Grant

• Current Assignee: Canon Ayutthaya Limited (Canon Inc.)
• Original Assignee: Canon Ayutthaya Limited (Canon Inc.)
• Inventors: Masumura, Takahiro
• Primary Examiner(s): Pham, Thomas K
• Assistant Examiner(s): BROOME, SHARRIEF I
• Application Number:
  US13/328,255
• Publication Number:
  US 20120182591A1
• Time in Patent Office: 1,180 Days
• Field of Search: 359 1- 15, 359/130, 359/224, 359/295, 359/230, 359/573, 359/21, 359/34, 359/35, 359/902, 356/479, 356/490, 356/495, 356/511, 356/512, 356/457, 356/458, 356/477, 356496-498
• US Class Current: 359/11
• CPC Class Codes: G01N 21/00 Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light G01N3/00 - G01N19/00 take precedence
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B
• CPC Class Codes: G01N 21/6456 Spatial resolved fluorescence measurements; Imaging
• CPC Class Codes: G01N 2201/0675 SLM
• CPC Class Codes: G02B 21/0032 Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers G02B21/0036 - G02B21/008; means for illumination of specimens in general G02B21/06
• CPC Class Codes: G02B 21/0052 Optical details of the image generation
• CPC Class Codes: G02B 21/0056 based on optical coherence, e.g. phase-contrast arrangements, interference arrangements
• CPC Class Codes: G02B 26/06 for controlling the phase of light G02B26/08 takes precedence , measuring optical phase difference G01J9/00
• CPC Class Codes: G03H 1/0443 Digital holography, i.e. recording holograms with digital recording means holobject computation G03H1/0866
• CPC Class Codes: G03H 2001/0072 for wavefront conjugation wherein the hologram generates a wavefront conjugating a predetermined object, e.g. null testing, positioning, comparative holography
• CPC Class Codes: G03H 2001/0083 for restoring distorted objects, e.g. restoring objects through scattering media
• CPC Class Codes: G03H 2001/0447 In-line recording arrangement
• CPC Class Codes: G03H 2001/0458 Temporal or spatial phase shifting, e.g. parallel phase shifting method
• CPC Class Codes: G03H 2001/0467 Gated recording using pulsed or low coherence light source, e.g. light in flight, first arriving light

Abstract

An apparatus includes a low-coherent light source configured to emit an electromagnetic wave; a spatial light modulator configured to modulate a wavefront of the electromagnetic wave; an interferometer including a movable mirror to set a depth of a medium to be irradiated by the electromagnetic wave and a beam splitter configured to the electromagnetic wave into a reference beam and an object beam; a detector to detect information about an interference pattern formed by the object beam coming from the medium via the beam splitter and the reference beam reflected by the movable mirror; and a controller configured to control the spatial light modulator, based on the information, to form a modulated wavefront for irradiating the medium.

Claims

1. An apparatus comprising:

a low-coherent light source for recording configured to emit an electromagnetic wave for recording;

a mirror which is movable;

a beam splitter configured to split the electromagnetic wave for recording into a reference beam heading for the mirror and an object beam heading for a medium;

a detector configured to detect an interference pattern formed by the object beam coming from the medium and the reference beam reflected by the mirror;

a light source for irradiation configured to emit an electromagnetic wave for irradiation; and

a spatial light modulator configured to modulate a wavefront of the electromagnetic wave for irradiation by using information about the interference pattern detected by the detector, so as to irradiate the medium with an electromagnetic wave for irradiation having the modulated wavefront,

wherein the mirror is configured to adjust an optical path length of the reference beam between the beam splitter and the detector, so as to set a specific depth inside the medium by matching the optical path length of the reference beam between the beam splitter and the detector with an optical path length of the object beam originated from the specific depth inside the medium between the beam splitter and the detector,

wherein the spatial light modulator modulates the electromagnetic wave for irradiation into a phase conjugation wave of the object beam originated from the specific depth inside the medium by using the information, and

wherein the phase conjugation wave travels back to the specific depth inside the medium set by the mirror.

2. The apparatus according to claim 1, wherein the low-coherent light source for recording is comprised of a super luminescent diode.

3. The apparatus according to claim 1, wherein the low-coherent light source for recording and the light source for irradiation are same light sources.

4. The apparatus according to claim 1, wherein the low-coherent light source for recording and the light source for irradiation are different light sources.

5. The apparatus according to claim 1, further comprising

a processing unit configured to generate an image using a signal generated by using the phase conjugation wave of the object beam originated from the specific depth inside the medium.

6. The apparatus according to claim 1, further comprising

a processing unit configured to generate an image using a photoacoustic signal generated by using the phase conjugation wave of the object beam originated from specific depth inside the medium.

7. An apparatus comprising:

a low-coherent light source for recording configured to emit an electromagnetic wave for recording;

a mirror which is movable;

a beam splitter configured to split the electromagnetic wave for recording into a reference beam heading for the mirror and an object beam heading for a medium;

a holographic material configured to record an interference pattern formed by the object beam coming from the medium and the reference beam reflected by the mirror; and

a light source for pumping arranged to irradiate the holographic material recording the interference pattern with an electromagnetic wave for pumping in a direction opposite to a direction of the reference beam, so that the holographic material generates a phase conjugation wave of the object wave,

wherein the mirror is configured to adjust an optical path length of the reference beam between the beam splitter and the holographic material, so as to set a specific depth inside the medium by matching the optical path length of the reference beam between the beam splitter and the detector with an optical path length of the object beam originated from the specific depth inside the medium between the beam splitter and the detector, and

wherein the holographic material generates the phase conjugation wave of the object beam originated from the specific depth inside the medium, which travels back to the specific depth inside the medium set by the mirror.

8. The apparatus according to claim 7, wherein the low-coherent light source for recording is comprised of a super luminescent diode.

9. The apparatus according to claim 7, wherein the low-coherent light source for recording and the light source for pumping are same light sources.

10. The apparatus according to claim 7, wherein the low-coherent light source for recording and the light source for pumping are different light sources.

11. The apparatus according to claim 7, further comprising

a processing unit configured to generate an image using a signal obtained by using the phase conjugation wave of the object beam originated from the specific depth inside the medium.

12. The apparatus according to claim 7, further comprising

a processing unit configured to generate an image using a photoacoustic signal obtained by using the phase conjugation wave of the object beam originated the from the specific depth inside the medium.