Spinal cord stimulation with interferential current

• US 8,977,363 B2
• Filed: 01/22/2004
• Issued: 03/10/2015
• Est. Priority Date: 01/22/2003
• Status: Active Grant

• Current Assignee: Meagan Medical, Inc.
• Original Assignee: Meagan Medical, Inc.
• Inventors: Carroll, William J., Terrell, Richard M.
• Primary Examiner(s): KAHELIN, MICHAEL WILLIAM
• Application Number:
  US10/761,424
• Publication Number:
  US 20040167584A1
• Time in Patent Office: 4,065 Days
• Field of Search: 607/67, 607 46- 47, 607/116
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/36192 Amplitude modulation
• CPC Class Codes: A61N 1/40 Applying electric fields by inductive or capacitive coupling microwave apparatus A61N5/00; Applying radio-frequency signals

Abstract

A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed in which implantable electrodes positioned around a targeted area of the spinal cord transmit an interferential current that has a base medium frequency alternating current between 500 Hz-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate at least two circuits for use in producing the interferential current. An effective area of stimulation is controlled by the quantity of electrodes, positioning of the electrodes and electrode cross pattern orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation. The stimulator and method reduce accommodation of the body to the electrical stimulation and provide deeper penetration of the resultant signal.

Claims

1. An electrical stimulator for the treatment of intractable pain syndromes, comprising:

an interferential current generator comprising a sine wave generator which generates an interferential alternating current output comprising first and second sinusoidal signals having different first and second frequencies with a base medium frequency of at least 500 Hz but no more than 20 KHz; and

at least two pairs of implantable electrodes wherein each electrode has a first and a second end, wherein the first ends are connected to said interferential current generator and the second ends are configured to be implanted to a dura matter in an epidural space at predetermined locations proximate to a subject'"'"'s spinal cord, wherein each pair of said at least two pairs of implantable electrodes transmits one of said first and second sinusoidal signals such that the first and second frequencies interfere with each other to produce at least one beat frequency signal proximate to the subject'"'"'s spinal cord, and wherein a majority of the at least one beat frequency signal is directionally distributed and controlled, enabling the at least one beat frequency signal to avoid remaining in and shunting through cerebrospinal fluid proximate to the subject'"'"'s spinal cord, thereby recruiting dorsal column fibers.

2. The stimulator of claim 1, wherein said interferential current generator comprises:

a pulse generator that generates digital signal pulses; and

a digital signal processor connected to said pulse generator that processes the digital signal pulses to approximate a sine-wave-like output waveform.

3. The stimulator of claim 1, wherein said interferential current generator comprises:

a pulse generator that generates digital signal pulses; and

a field-programmable gate array connected to said pulse generator that processes the digital signal pulses to approximate a sine-wave-like output waveform.

4. The stimulator of claim 1, wherein said interferential current includes a resultant beat frequency of no more than 250 Hz.

5. The stimulator of claim 1, wherein said interferential current includes a voltage output of 11 volts maximum for each circuit.

6. The stimulator of claim 1, wherein said interferential current includes a pulse width with a range of at least 10 microseconds but no more than 600 microseconds.

7. The stimulator of claim 1, wherein the at least two pairs of implantable electrodes comprise two quadripolar leads used to produce two interferential currents.

8. An electrical stimulator for the treatment of intractable pain syndromes, comprising:

an interferential current generator that generates an interferential alternating current output including first and second sinusoidal signals having different first and second frequencies, with a base medium frequency of at least 500 Hz but no more than 20 KHz; and

at least two pairs of implantable electrodes having first and second ends, wherein the first ends are connected to said interferential current generator and the second ends are configured to be implanted to a dura matter in an epidural space at predetermined locations proximate to a subject'"'"'s dorsal column, and

wherein each of said at least two pairs of implantable electrodes carries one of said first and second sinusoidal signals such that the first and second frequencies interfere with each other to produce at least one beat frequency signal proximate to the subject'"'"'s dorsal column, and wherein a majority of the at least one beat frequency signal is directionally distributed and controlled, enabling the at least one beat frequency signal to avoid remaining in and shunting through cerebrospinal fluid proximate to the subject'"'"'s dorsal column, thereby recruiting dorsal column fibers.

9. The stimulator of claim 8, wherein said interferential current generator comprises:

a pulse generator that generates digital signal pulses; and

a digital signal processor connected to said pulse generator that processes the digital signal pulses to approximate a sine-wave-like output waveform.

10. The stimulator of claim 8, wherein said interferential current generator comprises:

a pulse generator that generates digital signal pulses; and

a field-programmable gate array connected to said pulse generator that processes the digital signal pulses to approximate a sine-wave-like output waveform.

11. The stimulator of claim 8, wherein said interferential current includes a resultant beat frequency of no more than 250 Hz.

12. The stimulator of claim 8, wherein said interferential current includes a voltage output of 11 volts maximum for each circuit.

13. The stimulator of claim 8, wherein said interferential current includes a pulse width with a range of at least 10 microseconds but no more than 600 microseconds.

14. The stimulator of claim 8, wherein the at least two pairs of implantable electrodes comprise two quadripolar leads used to produce two interferential currents.