Methods of manufacturing devices for generating skin grafts

• US 8,978,234 B2
• Filed: 01/09/2012
• Issued: 03/17/2015
• Est. Priority Date: 12/07/2011
• Status: Active Grant

• Current Assignee: Solventum Intellectual Properties Company (Solventum Corp.)
• Original Assignee: MoMelan Technologies, Inc. (3M Company)
• Inventors: Sabir, Sameer Ahmed, Cerier, Jeffrey, Ziegler, Andrew
• Primary Examiner(s): Omgba, Essama
• Assistant Examiner(s): FORD, DARRELL CHRISTOPHER
• Application Number:
  US13/346,329
• Publication Number:
  US 20130145596A1
• Time in Patent Office: 1,163 Days
• Field of Search: 294/28, 294/53, 294/58, 295/25, 295/250.1, 295/251.3, 295/251.4, 295/271, 295/57, 295/58, 156/60, 606/132, 606/166, 606/131, 606/159, 606/161, 606167-174
• US Class Current: 29/525.14
• CPC Class Codes: A61B 17/322 Skin grafting apparatus
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2090/037 with a frangible part, e.g. by reduced diameter
• CPC Class Codes: A61B 2090/0814 Preventing re-use
• CPC Class Codes: A61B 90/03 Automatic limiting or abutting means, e.g. for safety
• CPC Class Codes: F04C 2270/041 Controlled or regulated
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 29/49826 Assembling or joining
• CPC Class Codes: Y10T 29/49885 with coating before or during assembling
• CPC Class Codes: Y10T 29/49945 by driven force fit
• CPC Class Codes: Y10T 29/49947 by applying separate fastener
• CPC Class Codes: Y10T 29/49966 with supplemental joining
• CPC Class Codes: Y10T 29/49968 Metal fusion joining
• CPC Class Codes: Y10T 29/4998 Combined manufacture including applying or shaping of fluent material

Abstract

The invention generally relates to methods for manufacturing components for use in a device for generating substantially planar micrografts. The methods of the invention provide for the manufacture of substantially uniform components for a cutter contained within the device, the cutter configured to cut a blister in order to produce a substantially planar graft.

Claims

1. A method for manufacturing a plurality of plates for use in a device for obtaining a skin graft, said method comprising the steps of:

obtaining a plurality of plates,

forming a plurality of openings in said plates such that the openings align upon stacking said plates; and

forming a plurality of coupling members in at least one of said plates, wherein said coupling members create at least a frangible linkage between at least two of said plates whereby the openings of the at least two plates can be maintained in alignment prior to use,

wherein said at least a frangible linkage is configured to break in response to application of a lateral force to at least one of said at least two plates to allow relative movement thereof.

2. The method of claim 1, wherein at least one of said one of more openings forms a cutting edge.

3. The method of claim 2, further comprising the step of attaching two or more plates together via said coupling members.

4. The method of claim 3, wherein one or more of said coupling members are disposed between at least two of said plates.

5. The method of claim 1, wherein said forming steps comprise laser etching, photo etching or lithographic processing.

6. The method of claim 5, wherein said frangible linkage is selected from a mechanical stamp, a mechanical punch, a weld, epoxy, an adhesive, mechanical compression, a snap-fit, a tongue and groove, a post and bar, or a frangible pin.

7. The method of claim 1, said coupling members are of substantially uniform shape and size.

8. The method of claim 1, further comprising the step of coupling two or more plates together via said coupling members.

9. The method of claim 1, further comprising removing a portion of material at or around a site of at least one of said coupling members to accommodate at least a portion of said coupling member.

10. The method of claim 9, wherein said plates are slidable with respect to each other upon breaking said frangible linkage.

11. The method of claim 1, wherein at least one of said plurality of plates comprises a substantially uniform thickness.

12. The method of claim 11, wherein said coupling members do not substantially alter said uniform thickness.

13. The method of claim 1, wherein said plurality of plates comprises a bottom plate, a middle plate and a top plate.

14. The method of claim 13, wherein said at least one frangible linkage couples said middle plate to any of said top and said bottom plate.

15. The method of claim 14, wherein upon breakage of said at least one frangible linkage the middle plate is configured to move relative to any of the top plate and the bottom plate within a fixed distance.

16. The method of claim 14, wherein said middle plate comprises any of at least a groove or a channel adapted to receive a pin vertically extending from the bottom plate, wherein the pin is received at one end of said groove or channel when said at least one frangible linkage is intact and is adapted to laterally slide to an opposite end of said groove or channel when said frangible linkage is broken.