Devices and systems for remote physiological monitoring
First Claim
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1. A wireless physiological monitoring device for monitoring physiological data, comprising:
- a substrate formed of a flexible material that is a biocompatible polymer, the substrate further comprising a first surface that is self-adhesive to affix the substrate to skin of a patient;
a wireless data transmission system embedded in the substrate that transmits the physiological data, the wireless data transmission system being a radio-frequency coil system having a coating of a biocompatible polymer material on a first side of the radio frequency coil system and on a second side of the radio frequency coil system and an insulating layer of polymer enclosed between a first and second metal layer, the wireless data transmission system configured to transmit the physiological data to a central monitoring station that is remotely positioned from the wireless physiological monitoring device;
a power source embedded in the substrate that generates power and that powers the wireless data transmission system;
a multi-electrode array embedded within the substrate to sense biopotentials at a site of application of the wireless physiological monitoring device from which to indicate physiological parameters;
a biosensor embedded in the substrate, the biosensor powered by the power source, to measure the physiological parameters;
wherein at least one of the wireless data transmission system, the power source, and the biosensor is microfabricated; and
a plurality of conductors embedded within the substrate to form flexible electrical interconnections among the data transmission system, the power source, and the biosensor;
wherein the wireless physiological monitoring device is non-invasive.
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Abstract
Devices and systems are provided for the remote monitoring of physiological parameters of a patient. An exemplary wireless physiological monitoring device comprises a substrate formed of a flexible biocompatible material. The substrate has a surface for affixing to the skin of a patient. A wireless data transmission device, a biosensor, and a power source are integrated with the substrate. The biosensor is configured to measure a physiological parameter. Flexible conductors are integrated with the substrate and are configured to electrically couple the biosensor and the power source with the data transmission device.
80 Citations
26 Claims
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1. A wireless physiological monitoring device for monitoring physiological data, comprising:
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a substrate formed of a flexible material that is a biocompatible polymer, the substrate further comprising a first surface that is self-adhesive to affix the substrate to skin of a patient; a wireless data transmission system embedded in the substrate that transmits the physiological data, the wireless data transmission system being a radio-frequency coil system having a coating of a biocompatible polymer material on a first side of the radio frequency coil system and on a second side of the radio frequency coil system and an insulating layer of polymer enclosed between a first and second metal layer, the wireless data transmission system configured to transmit the physiological data to a central monitoring station that is remotely positioned from the wireless physiological monitoring device; a power source embedded in the substrate that generates power and that powers the wireless data transmission system; a multi-electrode array embedded within the substrate to sense biopotentials at a site of application of the wireless physiological monitoring device from which to indicate physiological parameters; a biosensor embedded in the substrate, the biosensor powered by the power source, to measure the physiological parameters; wherein at least one of the wireless data transmission system, the power source, and the biosensor is microfabricated; and a plurality of conductors embedded within the substrate to form flexible electrical interconnections among the data transmission system, the power source, and the biosensor; wherein the wireless physiological monitoring device is non-invasive. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A wireless device for the remote monitoring of physiological parameters, the wireless device comprising:
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a substrate formed of at least one biocompatible polymer that is flexible, wherein the substrate comprises a first surface that is self-adhesive to affix the substrate to skin of a patient; a first multi-electrode array comprising electrode areas that are exposed through an exposure means selected from at least one of a photolithography technique and a plasma etching technique, wherein the multi-electrode array is embedded within the substrate; a self-contained power source embedded within the substrate that generates power and that powers the multi-electrode array; wherein the first multi-electrode array is powered by the power source and senses biopotentials at a site of application of the wireless device from which to indicate the physiological parameters; a wireless data transmission system embedded in the substrate that transmits the physiological data, the wireless data transmission system being a radio-frequency coil system having a coating of a biocompatible polymer material on a first side of the radio frequency coil system and on a second side of the radio frequency coil system and an insulating layer of polymer enclosed between a first and second metal layer, the wireless data transmission system configured to transmit the physiological data to a central monitoring station that is remotely positioned from the wireless physiological monitoring device; and wherein the wireless device is non-invasive. - View Dependent Claims (16, 17, 18, 19, 20, 21)
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22. A wireless physiological monitoring system for sustained monitoring of human military subjects moving under human power or vehicle transport, in a sustained movement condition, in a non-hospital environment, comprising:
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a wireless physiological monitoring device comprising; a substrate formed of a flexible material that is a biocompatible polymer, the substrate further comprising a first surface that is self-adhesive to affix the substrate to skin of a patient; a wireless data transmission system embedded in the substrate that transmits physiological parameters, the wireless data transmission system being a radio-frequency coil system having a coating of a biocompatible polymer material on a first side of the radio frequency coil system and on a second side of the radio frequency coil and an insulating layer of polymer enclosed between a first and second metal layer; a multi-electrode array embedded within the substrate to sense biopotentials at a site of application of the wireless physiological monitoring device from which to indicate physiological parameters; a self-contained power source embedded in the substrate that powers the wireless data transmission system; a biosensor embedded in the substrate, the biosensor powered by the power source to measure the physiological parameters; wherein at least one of the wireless data transmission system, the power source, and the biosensor is microfabricated; and a plurality of flexible conductors embedded within the substrate to form flexible electrical interconnections among the data transmission system, the power source, and the biosensor; and a central monitoring station comprising a transceiver that receives physiological parameters transmitted wirelessly by the wireless physiological monitoring device, wherein the central monitoring station is remotely positioned from the wireless data transmission system; wherein the wireless physiological monitoring device is non-invasive. - View Dependent Claims (23, 24, 25)
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26. A wireless physiological monitoring device comprising:
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a substrate formed of a flexible biocompatible material, the substrate comprising a surface to affix the substrate to skin of a patient; a multi-electrode array embedded within the substrate to sense biopotentials at a site of application of the wireless physiological monitoring device from which to indicate physiological parameters, the multi-electrode array comprising electrode areas that are exposed through an exposure means selected from at least one of a photolithography technique and a plasma etching technique; a wireless data transmission device integrated with the substrate to transmit the physiological parameters, the wireless data transmission device being a radio-frequency coil system having a coating of a biocompatible polymer material on a first side of the radio frequency coil system and on a second side of the radio frequency coil system and an insulating layer of polymer enclosed between a first and second metal layer; a power source integrated with the substrate to power one or more of the multi-electrode array and the wireless data transmission device; and flexible conductors embedded within the substrate and configured to electrically couple the multi-electrode array and the power source with the data transmission device; wherein at least one of the wireless data transmission device and the power source is microfabricated.
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Specification