Method and device for clamping a blister within a dry powder inhaler

• US 8,985,101 B2
• Filed: 03/15/2013
• Issued: 03/24/2015
• Est. Priority Date: 05/21/2009
• Status: Active Grant

• Current Assignee: MicroDose Therapeutx, Inc. (Teva Pharmaceutical Industries Limited)
• Original Assignee: MicroDose Therapeutx, Inc. (Teva Pharmaceutical Industries Limited)
• Inventors: Mosier, Kent D.
• Primary Examiner(s): Hand, Melanie
• Assistant Examiner(s): Heffner, Ned T
• Application Number:
  US13/840,577
• Publication Number:
  US 20130213392A1
• Time in Patent Office: 739 Days
• Field of Search: 128/203.12, 128/203.15, 128/203.19, 128/203.21, 12820011-20023, 128/3.15, 604/58, 604 9301- 9501, 604/403, 222/144, 222/168.5, 222167-168
• US Class Current: 128/203.12
• CPC Class Codes: A61M 11/005 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 15/001 using ultrasonic means
• CPC Class Codes: A61M 15/0025 with caps
• CPC Class Codes: A61M 15/0035 Piercing means
• CPC Class Codes: A61M 15/0041 with movable piercing or cutting means
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 15/0061 using pre-packed dosages having an insert inside
• CPC Class Codes: A61M 15/0063 Storages for pre-packed dosages
• CPC Class Codes: A61M 15/0083 Timers
• CPC Class Codes: A61M 15/0085 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 15/0091 mechanically breath-triggered
• CPC Class Codes: A61M 2016/0024 with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2016/0033 electrical
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 2205/8206 battery-operated

Abstract

The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein individual blister packs are positioned within the housing to be simultaneously engaged with the flow channel and the vibration element. The flow channel includes a blister pack clamping surface that engages the blister pack near the top of the crown and allows the blister three rotational degrees of freedom. The advantages of this arrangement include improved consistency and higher airspeed of the synthetic jet, as well as other advantages.

Claims

1. A medication inhaler, comprising

a housing for accommodating a cartridge including a rotary carousel containing a plurality of individual separate blister packs fanned out in a radial pattern relative to a plane of the rotary carousel, wherein said individual blister packs each contain a medication;

a vibrating element within the housing;

a blister pack carrier for moving one blister pack at a time along a radial path into an operating position adjacent a chamber;

said chamber defining a flow channel communicating with a blister pack, wherein the chamber includes a blister clamping surface to which an individual, separate blister pack may be clamped in position adjacent the vibrating element, said blister clamping surface comprising an opening through which the blister pack engages at least in part with the chamber; and

a spring for urging the vibrating element against the individual blister pack.

2. The inhaler of claim 1, wherein the blister pack comprises a first face and a second face, the second face being positioned in contact with the vibrating element.

3. The inhaler of claim 1, wherein the vibrating element is a piezoelectric transducer.

4. The inhaler of claim 1, wherein the medication comprises a dry powder.

5. The inhaler of claim 1, wherein the medication comprises a liquid.

6. The inhaler of claim 1, further comprising a flow sensor for sensing the breath of the user, and an electrical circuit for activating the vibrating element.

7. The inhaler of claim 1, further comprising a battery and a printed circuit board.

8. The inhaler of claim 1, wherein the blister pack comprises a first face and a second face, the first face having a crown, the first face being engaged at least in part with the chamber.

9. The inhaler of claim 8, wherein the blister clamping surface allows three rotational degrees of freedom between the chamber and the blister pack.

10. The inhaler of claim 8, wherein the blister clamping surface surrounds, at least in part, the crown of the blister pack.

11. The inhaler of claim 10, wherein the blister clamping surface engages the first face of the blister pack that is closer to the top of the crown than to the base of the crown.