Apparatus administering a therapeutic agent into tissue

• US 8,986,520 B2
• Filed: 03/11/2013
• Issued: 03/24/2015
• Est. Priority Date: 06/15/2004
• Status: Expired due to Term

• Current Assignee: ActiveO, Inc.
• Original Assignee: Ceramatec, Inc. (Trelleborg AB)
• Inventors: Joshi, Ashok V., Steppan, James, Nachlas, Jesse, Murphy, Kieran
• Primary Examiner(s): Mayekar, Kishor
• Application Number:
  US13/793,889
• Publication Number:
  US 20130220801A1
• Time in Patent Office: 743 Days
• Field of Search: 204/280, 204/275.1, 422/186.07, 422/186.12, 604/25
• US Class Current: 204/275.1
• CPC Class Codes: A61B 17/3478 Endoscopic needles, e.g. for infusion biopsy needles A61B10/0233; catheters with injection needles A61M25/0067
• CPC Class Codes: A61B 2017/00261 Discectomy
• CPC Class Codes: A61M 2005/006 for gases, e.g. CO2
• CPC Class Codes: A61M 2005/3132 having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
• CPC Class Codes: A61M 2202/0216 Ozone
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61M 5/286 upon internal pressure increase, e.g. pierced or burst A61M5/283 takes precedence
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: C01B 13/02 Preparation of oxygen by liquefying F25J
• CPC Class Codes: C01B 13/10 Preparation of ozone
• CPC Class Codes: C25B 1/13 Ozone

Abstract

An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes an ozone generator for producing therapeutic oxygen-ozone mixture. The generator includes an electrochemical cell configured to communicate with an accumulator having an anode, a cathode and a power supply in electrical communication with the anode and the cathode. The power supply is configured to create an electric current between the anode and the cathode such that water in the electrochemical cell electrolyzes to produce ozone and oxygen at the anode.

Claims

1. An ozone generator for producing a therapeutic oxygen-ozone mixture, the ozone generator comprising:

a chamber;

an electrochemical cell within the chamber comprising an anode and a cathode;

a power supply within the chamber in electrical communication with the anode and the cathode, the power supply configured to create an electric current between the anode and the cathode to electrolyze water and thereby produce an ozone-oxygen mixture;

an accumulator within the chamber to receive the ozone-oxygen mixture from the electrochemical cell; and

a release mechanism within the chamber to release the ozone-oxygen mixture from the accumulator when the ozone-oxygen mixture reaches a designated amount.

2. The ozone generator of claim 1, wherein water is electrolyzed at the anode to produce the oxygen-ozone mixture.

3. The ozone generator of claim 1, wherein the release mechanism comprises a piercing member to pierce the accumulator when the accumulator reaches the designated size.

4. The ozone generator of claim 1, wherein the release mechanism comprises a moveable stopper and channel to enable the ozone-oxygen mixture to flow out of the accumulator when the accumulator reaches the designated size.

5. The ozone generator of claim 1, wherein the accumulator comprises a resiliently deformable balloon.

6. The ozone generator of claim 1, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen, wherein the ratio ranges from about five to about one-hundred.

7. The ozone generator of claim 6, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen, wherein the ratio ranges from about twelve to about forty.

8. The ozone generator of claim 7, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen of about twenty.

9. An ozone generator for producing ozone, the ozone generator comprising:

a chamber;

an electrochemical cell within the chamber configured to produce ozone;

a power supply within the chamber in electrical communication with the electrochemical cell;

an accumulator within the chamber to receive the ozone from the electrochemical cell; and

a release mechanism within the chamber to release the ozone from the accumulator when the accumulator reaches a designated size, the release mechanism comprising one of a piercing member to pierce the accumulator, and a moveable stopper and channel to enable the ozone to flow out of the accumulator.

10. The ozone generator of claim 9, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen, wherein the ratio ranges from about five to about one-hundred.

11. The ozone generator of claim 10, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen, wherein the ratio ranges from about twelve to about forty.

12. The ozone generator of claim 11, wherein the electrochemical cell is configured to create a ratio of micrograms of ozone to cubic centimeters of oxygen of about twenty.