Cassette system integrated apparatus

• US 8,992,189 B2
• Filed: 09/14/2012
• Issued: 03/31/2015
• Est. Priority Date: 02/27/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Wilt, Michael J., Grant, Kevin L., Dale, James D., Demers, Jason A., Tracey, Brian D.
• Primary Examiner(s): LETTMAN, BRYAN MATTHEW
• Application Number:
  US13/619,343
• Publication Number:
  US 20130022483A1
• Time in Patent Office: 928 Days
• Field of Search: 417/323, 417/379, 417/392, 417/394, 417/395, 417/413.1, 417/439, 417/440, 417/442, 417/479, 417/521, 210/645, 210/646, 604/6.11
• US Class Current: 417/413.1
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1563 Details of incorporated filters
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1658 Degasification
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/268 the displacement member being flexible, e.g. membranes, diaphragms or bladders
• CPC Class Codes: A61M 60/37 : Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/427 : the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/523 : using blood flow data, e.g. from blood flow transducers
• CPC Class Codes: A61M 60/546 : of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 43/02 : having plate-like flexible members, e.g. diaphragms F04B43/14 takes precedence
• CPC Class Codes: F04B 43/06 : Pumps having fluid drive
• CPC Class Codes: F04B 43/073 : the actuating fluid being controlled by at least one valve
• CPC Class Codes: F04B 43/0733 : with fluid-actuated pump inlet or outlet valves; with two or more pumping chambers in series
• CPC Class Codes: F04B 45/053 : Pumps having fluid drive
• CPC Class Codes: F04B 45/0536 : the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 53/106 : the valve being a membrane
• CPC Class Codes: F04B 53/1062 : fixed at two or more points at its periphery
• CPC Class Codes: F04B 9/109 : having plural pumping chambers
• CPC Class Codes: F16K 99/0015 : Diaphragm or membrane valves
• CPC Class Codes: Y10T 137/0329 : Mixing of plural fluids of diverse characteristics or conditions
• CPC Class Codes: Y10T 137/2521 : Flow comparison or differential response
• CPC Class Codes: Y10T 137/2931 : Diverse fluid containing pressure systems
• CPC Class Codes: Y10T 137/7879 : Resilient material valve
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/86139 : Serial

Abstract

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Claims

1. A pumping cassette comprising:

a housing comprising at least two fluid lines comprising a first inlet fluid line and a first outlet fluid line for a first liquid, and a second inlet fluid line and a second outlet fluid line for a second liquid;

at least one balancing pod within said housing and in fluid connection with said fluid lines, said balancing pod comprising a first chamber separated from a second chamber by a first flexible membrane, the first chamber in fluid connection with the first line, and the second chamber in fluid connection with the second line, wherein said balancing pod balances the flow of the first fluid with the flow of the second fluid; and

at least one reciprocating positive displacement membrane pump within said housing, said membrane pump having an interior cavity comprising an actuation chamber separated from a pumping chamber by a second flexible membrane, wherein a stroke of said membrane pump is configured to pump a first volume of the second fluid to the second chamber of the balancing pod, displacing the first volume of the first fluid from the first chamber of the balancing pod.

2. The cassette claimed in claim 1 wherein said at least one reciprocating positive displacement pumps comprises:

a curved rigid chamber wall; and

wherein

said second flexible membrane is attached to said rigid chamber wall, wherein said second flexible membrane and said rigid chamber wall define a pumping chamber.

3. The cassette claimed in claim 1, wherein said housing further comprises:

a top plate;

a midplate; and

a bottom plate.

4. The cassette claimed in claim 1, further comprising a metering pump within said housing and fluidly connected to said first or second fluid lines, wherein said metering pump is configured to pump fluid to bypass the balancing pod.

5. The cassette of claim 4, wherein said membrane pump and said metering pump are pneumatically actuated pumps.

6. The cassette claimed in claim 1, further comprising a metering pump within said housing and fluidly connected to said first or second fluid lines, wherein said metering pump is a reciprocating positive displacement membrane pump configured to pump fluid to bypass the balancing pod.

7. The cassette of claim 1 further comprising at least one fluid valve in each of the fluid lines.

8. The cassette of claim 7 wherein said cassette comprises at least two fluid valves that are actuated by one pneumatic valve.